{"id":1904,"date":"2025-10-13T09:59:16","date_gmt":"2025-10-13T09:59:16","guid":{"rendered":"https:\/\/ardenneiratherm.com\/clinical-trials-whole-body-hyperthermia-wira\/"},"modified":"2026-01-15T10:22:19","modified_gmt":"2026-01-15T10:22:19","slug":"clinical-research","status":"publish","type":"page","link":"https:\/\/ardenneiratherm.com\/ja\/clinical-research\/","title":{"rendered":"\u81e8\u5e8a\u8a66\u9a13"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1904\" class=\"elementor elementor-1904 elementor-756\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ea8f7b2 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"ea8f7b2\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInDown&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f3c7e79 elementor-widget elementor-widget-heading\" data-id=\"f3c7e79\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">\u816b\u760d\u5b66\u304a\u3088\u3073\u4ed6\u75be\u60a3\u306b\u304a\u3051\u308b\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08WBH\uff09\uff1a\u78ba\u7acb\u3055\u308c\u305f\u76f8\u4e57\u52b9\u679c\u3001\u514d\u75ab\u8abf\u7bc0\u3001\u304a\u3088\u3073\u81e8\u5e8a\u7684\u30a8\u30d3\u30c7\u30f3\u30b9<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c02c88e animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"c02c88e\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 800px; margin: 0 auto; text-align: center; font-family: sans-serif; line-height: 1.6;\"><header style=\"margin-bottom: 20px;\">\n<p style=\"margin-bottom: 5px;\"><strong><span style=\"color: #6a6a6a; font-size: 14px;\">\u516c\u958b\u65e5\uff1a<time datetime=\"2025-10-13\">2025\u5e7410\u670813\u65e5<\/time> | \u6700\u7d42\u66f4\u65b0\u65e5\uff1a<time datetime=\"2025-10-13\">2025\u5e7410\u670813\u65e5<\/time><\/span><\/strong><\/p>\n\n<div style=\"font-size: 16px; color: #333;\">\u8457\u8005\n<a style=\"text-decoration: none; color: #007bff;\" href=\"\/?p=139\">Veronica Iatan, MD<\/a>,\n<a style=\"text-decoration: none; color: #007bff;\" href=\"\/?p=137\">Cristian Gologan, M.Sc.<\/a><\/div>\n<\/header>\n\n<hr style=\"border: 0; height: 1px; background: #eee; margin: 25px 0;\" \/>\n\n<section style=\"background-color: #f9f9f9; padding: 25px; border-radius: 10px; border-left: 4px solid #007bff; margin-bottom: 25px;\">\n<p style=\"font-weight: bold; font-style: italic; font-size: 18px; color: #2c3e50; margin: 0;\">\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08WBH\uff09\u306f\u3001\u6c34\u30d5\u30a3\u30eb\u30bf\u578b\u8d64\u5916\u7ddaA\u6ce2\uff08wIRA\uff09\u6280\u8853\u306a\u3069\u3092\u7528\u3044\u3066\u6df1\u90e8\u4f53\u6e29\u3092\u5236\u5fa1\u3057\u306a\u304c\u3089\u4e0a\u6607\u3055\u305b\u308b\u5168\u8eab\u7684\u306a\u816b\u760d\u6cbb\u7642\u6226\u7565\u3067\u3059\u3002WBH\u306f\u6839\u672c\u7684\u306b\u5316\u5b66\u7642\u6cd5\u3084\u653e\u5c04\u7dda\u7642\u6cd5\u306e\u611f\u53d7\u6027\u5897\u611f\u5264\u3068\u3057\u3066\u6a5f\u80fd\u3057\u3001\u816b\u760d\u306e\u8840\u6d41\u3068\u9178\u7d20\u5316\u3092\u6709\u610f\u306b\u6539\u5584\u3059\u308b\u3053\u3068\u3067\u3001\u5f93\u6765\u6cbb\u7642\u306e\u52b9\u679c\u3092\u5897\u5e45\u3055\u305b\u307e\u3059\u3002\u6975\u3081\u3066\u91cd\u8981\u306a\u70b9\u3068\u3057\u3066\u3001WBH\u306f\u5f37\u529b\u306a\u5168\u8eab\u6027\u514d\u75ab\u8abf\u7bc0\u56e0\u5b50\u3068\u3057\u3066\u4f5c\u7528\u3057\u3001\u71b1\u30b7\u30e7\u30c3\u30af\u30bf\u30f3\u30d1\u30af\u8cea\uff08HSP\uff09\u3084T\u7d30\u80de\u3092\u52d5\u54e1\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u6700\u5148\u7aef\u306e\u514d\u75ab\u7642\u6cd5\uff08ICI\uff09\u3068\u306e\u4e0d\u53ef\u6b20\u306a\u76f8\u4e57\u52b9\u679c\u3092\u751f\u307f\u51fa\u3059\u3068\u3068\u3082\u306b\u3001\u69d8\u3005\u306a\u304c\u3093\u3084\u7dda\u7dad\u7b4b\u75db\u75c7\u306a\u3069\u306e\u6162\u6027\u75be\u60a3\u306b\u304a\u3044\u3066\u3001\u5287\u7684\u304b\u3064\u8fc5\u901f\u306a\u75bc\u75db\u7de9\u548c\u3068QOL\uff08\u751f\u6d3b\u306e\u8cea\uff09\u306e\u5411\u4e0a\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002<\/p>\n\n<\/section><section style=\"padding: 15px; border: 1px dashed #ccc; border-radius: 6px; background-color: #fff;\">\n<p style=\"font-size: 13px; color: #777; margin: 0; line-height: 1.4;\"><strong>* \u514d\u8cac\u4e8b\u9805\uff1a<\/strong> \u672c\u8a18\u4e8b\u306f\u60c5\u5831\u63d0\u4f9b\u306e\u307f\u3092\u76ee\u7684\u3068\u3057\u3066\u304a\u308a\u3001\u533b\u5e2b\u306b\u3088\u308b\u500b\u5225\u306e\u8a3a\u5bdf\u3001\u8a3a\u65ad\u3001\u307e\u305f\u306f\u6cbb\u7642\u306b\u4ee3\u308f\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n<\/section><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-805e6aa e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"805e6aa\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-67bd9be elementor-widget elementor-widget-heading\" data-id=\"67bd9be\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">1. \u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08WBH\uff09\u306e\u5b9a\u7fa9\u3068\u6cbb\u7642\u6280\u8853<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-67346b0 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"67346b0\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n\n<strong>\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08WBH\uff09<\/strong>\u3001\u307e\u305f\u306f\u300c\u5168\u8eab\u6e29\u71b1\u7642\u6cd5\u300d\u306f\u3001\u6cbb\u7642\u76ee\u7684\u3067\u8eab\u4f53\u306e\u6df1\u90e8\u4f53\u6e29\u3092\u5236\u5fa1\u3057\u306a\u304c\u3089\u4e0a\u6607\u3055\u305b\u308b\u3053\u3068\u3068\u5b9a\u7fa9\u3055\u308c\u3066\u3044\u307e\u3059\u3002<strong>\u7570\u306a\u308b\u6e29\u5ea6\u306b\u304a\u3051\u308b\u81ea\u7136\u306a\u767a\u71b1\u306e\u52b9\u679c<\/strong>\u306e\u30b9\u30da\u30af\u30c8\u30eb\u306b\u57fa\u3065\u304d\u3001WBH\u306e\u624b\u9806\u306f\u6b21\u306e\u3088\u3046\u306b\u533a\u5206\u3055\u308c\u307e\u3059\u3002\n\n<div style=\"background: #f4f7f9; padding: 20px; border-radius: 8px; margin: 20px 0; border-left: 5px solid #007bff;\"> <ul style=\"list-style: none; padding-left: 0; margin: 0; font-size: 1.1em;\"> \u00a0 <li style=\"margin-bottom: 8px;\"><strong>\u2022 \u8efd\u5ea6 WBH:<\/strong> &lt; 38.5\u00b0C<\/li> \u00a0 <li style=\"margin-bottom: 8px;\"><strong>\u2022 \u4e2d\u7b49\u5ea6 WBH:<\/strong> 38.5\u00b0C \u2013 40.5\u00b0C<\/li> \u00a0 <li><strong>\u2022 \u9ad8\u5ea6 WBH:<\/strong> &gt; 40.5\u00b0C<\/li> <\/ul> <\/div> \u7279\u306b\u8efd\u5ea6\u304a\u3088\u3073\u4e2d\u7b49\u5ea6\u306eWBH\u306f\u3001<strong>\u8840\u6d41\u3092\u5897\u52a0<\/strong>\u3055\u305b\u3001\u4ee3\u8b1d\u3092\u4fc3\u9032\u3057\u3001\u7b4b\u7dca\u5f35\u3092\u7de9\u548c\u3059\u308b\u3068\u3068\u3082\u306b\u3001<strong>\u514d\u75ab\u7cfb\u3092\u523a\u6fc0<\/strong>\u3057\u307e\u3059\u3002\n\n<a style=\"color: #007bff; text-decoration: none;\" title=\"Technical details von Ardenne IRATHERM\u00ae 1000M WBH wIRA device\" href=\"\/?page_id=270\"><strong>\u30d5\u30a9\u30f3\u30fb\u30a2\u30eb\u30c7\u30f3\u30cc IRATHERM\u00ae 1000M WBH wIRA \u88c5\u7f6e<\/strong><\/a>\u306f\u3001\u3053\u306e\u76ee\u7684\u306e\u305f\u3081\u306b\u3001<strong>\u808c\u306b\u512a\u3057\u304f\u6df1\u90e8\u7d44\u7e54\u307e\u3067\u5230\u9054\u3059\u308b\u6c34\u30d5\u30a3\u30eb\u30bf\u578b\u8d64\u5916\u7ddaA\u6ce2\uff08wIRA\uff09\u71b1\u653e\u5c04<\/strong>\uff08IR-B \/ IR-C\u3092\u542b\u307e\u306a\u3044\uff09\u306e\u307f\u3092\u72ec\u5360\u7684\u306b\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u9589\u6240\u6050\u6016\u75c7\u3092\u611f\u3058\u3055\u305b\u306a\u3044\u30aa\u30fc\u30d7\u30f3\u30b7\u30b9\u30c6\u30e0\u8a2d\u8a08\u306b\u3088\u308a\u3001\u60a3\u8005\u306e\u80cc\u9762\u5168\u4f53\u306b\u5747\u4e00\u306a\u7167\u5c04\u5f37\u5ea6\u3092\u78ba\u4fdd\u3057\u3001\u30e6\u30fc\u30b6\u30fc\u306f\u60a3\u8005\u3054\u3068\u306b\u6700\u9069\u5316\u3055\u308c\u305f\u71b1\u4f9b\u7d66\u3092\u884c\u3046\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\n\n\u6c34\u30d5\u30a3\u30eb\u30bf\u578b\u8d64\u5916\u7ddaA\u6ce2\u653e\u5c04\u306f\u592a\u967d\u306e\u81ea\u7136\u306a\u71b1\u653e\u5c04\u306b\u5bfe\u5fdc\u3057\u3066\u304a\u308a\u3001\u5747\u4e00\u3067\u7a4f\u3084\u304b\u306a\u71b1\u306e\u9069\u7528\u3092\u53ef\u80fd\u306b\u3059\u308b\u6280\u8853\u7684\u57fa\u76e4\u3092\u63d0\u4f9b\u3057\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[1, 5, 7, 8]<\/span>\u3002\n\n30\u5e74\u4ee5\u4e0a\u306b\u308f\u305f\u308a\u5b9f\u8a3c\u3055\u308c\u3066\u304d\u305f\u30d5\u30a9\u30f3\u30fb\u30a2\u30eb\u30c7\u30f3\u30cc IRATHERM\u00ae \u306e\u539f\u7406\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u3001<a style=\"color: #007bff; text-decoration: none;\" title=\"Prof. Manfred von Ardenne - Contributions\" href=\"\/?p=5\">\u30de\u30f3\u30d5\u30ec\u30fc\u30c8\u30fb\u30d5\u30a9\u30f3\u30fb\u30a2\u30eb\u30c7\u30f3\u30cc\u6559\u6388<\/a>\u306f\u3001\u3053\u306e\u71b1\u653e\u5c04\u3092\u7269\u7406\u7684\u30fb\u6280\u8853\u7684\u306b\u518d\u73fe\u3059\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u3001\u816b\u760d\u5b66\u304a\u3088\u3073\u305d\u306e\u4ed6\u306e\u75c5\u7406\u306b\u304a\u3051\u308b\u6301\u7d9a\u53ef\u80fd\u306a\u533b\u7642\u5229\u7528\u3092\u53ef\u80fd\u306b\u3057\u307e\u3057\u305f\u3002\n\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6c924fa elementor-invisible elementor-widget elementor-widget-image\" data-id=\"6c924fa\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;zoomIn&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/ardenneiratherm.com\/wp-content\/uploads\/2025\/10\/von-Ardenne-Iratherm-10000-WBH-wIRA-hyperthermia-device-wIRA.jpg\" title=\"\" alt=\"von Ardenne Iratherm 10000 WBH wIRA hyperthermia-device-wIRA\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-48fd6d3 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"48fd6d3\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-aafa804 elementor-widget elementor-widget-heading\" data-id=\"aafa804\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">2. \u79d1\u5b66\u7684\u6839\u62e0\u3068\u5168\u8eab\u3078\u306e\u5f71\u97ff<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-672df30 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"672df30\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n\nWBH\u306f\u3001\u78ba\u56fa\u305f\u308b\u751f\u7269\u7269\u7406\u5b66\u7684\u304a\u3088\u3073\u751f\u7406\u5b66\u7684\u539f\u7406\u306b\u57fa\u3065\u3044\u305f\u6226\u7565\u3078\u3068\u9032\u5316\u3092\u9042\u3052\u307e\u3057\u305f\u3002\u816b\u760d\u5b66\u306b\u304a\u3044\u3066\u306f\u3001<strong>\u4e2d\u7b49\u5ea6<\/strong>\u304a\u3088\u3073<strong>\u767a\u71b1\u57df\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08FR-WBH\uff09<\/strong>\u306b\u7126\u70b9\u304c\u5f53\u3066\u3089\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306f\u8907\u6570\u306e\u6cbb\u7642\u9069\u5fdc\u3092\u6301\u3064\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[1, 3]<\/span>\u3002\n\n\u5747\u4e00\u304b\u3064\u7a4f\u3084\u304b\u306a\u71b1\u9069\u7528\u306e\u305f\u3081\u306e\u6280\u8853\u7684\u57fa\u76e4\u306f\u3001\u591a\u304f\u306e\u5834\u5408\u3001<strong>\u6c34\u30d5\u30a3\u30eb\u30bf\u578b\u8d64\u5916\u7ddaA\u6ce2\uff08wIRA\uff09\u653e\u5c04<\/strong>\u3092\u7528\u3044\u308b\u88c5\u7f6e\u306b\u3088\u3063\u3066\u63d0\u4f9b\u3055\u308c\u307e\u3059\u3002\u8a73\u7d30\u306a\u751f\u7269\u7269\u7406\u5b66\u7684\u7814\u7a76\u306b\u3088\u308a\u3001\u76ae\u819a\u306e\u5149\u5b66\u7279\u6027\u3084\u7dda\u91cf\u6e2c\u5b9a\u306e\u5149\u751f\u7269\u5b66\u7684\u57fa\u790e\u3092\u8003\u616e\u3057\u305f\u4e0a\u3067\u3001\u3053\u306e<strong>\u6280\u8853\u304c\u6df1\u90e8\u304b\u3064\u5236\u5fa1\u3055\u308c\u305f\u52a0\u71b1\u3092\u78ba\u5b9f\u306b\u884c\u3048\u308b\u80fd\u529b<\/strong>\u304c\u691c\u8a3c\u3055\u308c\u3066\u3044\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[5, 7, 8]<\/span>\u3002\n\n\u751f\u7406\u5b66\u7684\u30ec\u30d9\u30eb\u306b\u304a\u3044\u3066\u3001WBH\u306b\u306f\u57fa\u672c\u7684\u306a\u5168\u8eab\u7684\u5f71\u97ff\u304c\u3042\u308a\u307e\u3059\uff1a\n\n<div style=\"background: #ffffff; padding: 20px; border: 1px solid #eef2f6; border-radius: 10px; box-shadow: 0 2px 8px rgba(0,0,0,0.05); margin: 25px 0;\">\n<ol style=\"padding-left: 20px; margin: 0;\">\n\u00a0\t<li style=\"margin-bottom: 15px;\"><strong style=\"color: #007bff; font-size: 1.1em;\">\u8840\u6db2\u6d41\u52d5\u6027\u306e\u6539\u5584\uff1a<\/strong>\nIR-WBH\u3078\u306e\u66dd\u9732\u306f\u3001<strong>\u8840\u6db2\u306e\u6d41\u52d5\u7279\u6027\u3068\u8840\u6db2\u52d5\u614b<\/strong>\u306b\u597d\u307e\u3057\u3044\u5f71\u97ff\u3092\u4e0e\u3048 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[2]<\/span>\u3001\u5168\u8eab\u6cbb\u7642\u3092\u6210\u529f\u3055\u305b\u308b\u305f\u3081\u306e\u91cd\u8981\u306a\u524d\u63d0\u6761\u4ef6\u3067\u3042\u308b<strong>\u816b\u760d\u8840\u6d41\u306e\u6539\u5584<\/strong>\u3068\u3044\u3046\u4e0d\u53ef\u6b20\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u652f\u3048\u307e\u3059\u3002<\/li>\n\u00a0\t<li><strong style=\"color: #007bff; font-size: 1.1em;\">\u5168\u822c\u7684\u306a\u751f\u7269\u5b66\u7684\u6d3b\u6027\u5316\uff1a<\/strong>\nWBH\u306f\u71b1\u30b9\u30c8\u30ec\u30b9\u53cd\u5fdc\u3092\u8a98\u767a\u3057\u3001<strong>\u30db\u30eb\u30e2\u30f3\u7cfb\u306e\u8abf\u7bc0<\/strong>\u3084<strong>\u4ee3\u8b1d\u306e\u4fc3\u9032<\/strong>\u3092\u542b\u3080\u4e00\u9023\u306e\u751f\u7269\u5b66\u7684\u30d7\u30ed\u30bb\u30b9\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[6, 4]<\/span>\u3002<\/li>\n<\/ol>\n<\/div>\n\u3053\u308c\u3089\u306e\u57fa\u790e\u306b\u3088\u308a\u3001WBH\u306f<strong>\u5168\u8eab\u6027\u514d\u75ab\u8abf\u7bc0\u56e0\u5b50<\/strong>\u3068\u3057\u3066\u6a5f\u80fd\u3057\u3001<strong>\u816b\u760d\u5fae\u5c0f\u74b0\u5883\uff08TME\uff09<\/strong>\u3092\u6700\u9069\u5316\u3057\u3066\u3001<strong>\u6700\u5148\u7aef\u306e\u816b\u760d\u6cbb\u7642\u306e\u52b9\u679c\u3092\u5897\u5e45<\/strong>\u3055\u305b\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[9]<\/span>\u3002\n\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-73d38c1 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"73d38c1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4061817 elementor-widget elementor-widget-heading\" data-id=\"4061817\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">3. \u4f5c\u7528\u6a5f\u5e8f\u306e\u9375\uff08\u5206\u5b50\u3001\u751f\u7406\u3001\u304a\u3088\u3073\u514d\u75ab\u5b66\u7684\u30e1\u30ab\u30cb\u30ba\u30e0\uff09<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-22327e2 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"22327e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n<p style=\"font-size: 1.1em; border-left: 4px solid #007bff; padding-left: 15px; margin-bottom: 25px;\">WBH\u306e\u6cbb\u7642\u52b9\u679c\u306f\u3001<strong>\u7d30\u80de\u3001\u514d\u75ab\u3001\u304a\u3088\u3073\u751f\u7406\u5b66\u7684\u30ec\u30d9\u30eb<\/strong>\u306e\u5909\u5316\u3092\u4ecb\u3057\u305f\u8907\u96d1\u306a\u3082\u306e\u3067\u3059\uff1a<\/p>\n\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5638fef animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"5638fef\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n<h3 style=\"text-align: left; color: #2c3e50; border-bottom: 2px solid #eef2f6; padding-bottom: 10px; margin-top: 30px;\">A. \u5316\u5b66\u7642\u6cd5\u304a\u3088\u3073\u653e\u5c04\u7dda\u7642\u6cd5\u3068\u306e\u76f8\u4e57\u52b9\u679c\uff08\u5316\u5b66\/\u653e\u5c04\u7dda\u611f\u53d7\u6027\u5897\u611f\u5264\uff09<\/h3>\n<ul style=\"padding-left: 20px; list-style-type: square;\">\n\u00a0\t<li style=\"margin-bottom: 15px; text-align: left;\"><strong>\u816b\u760d\u5fae\u5c0f\u74b0\u5883\uff08TME\uff09\u306e\u6700\u9069\u5316\uff1a<\/strong> WBH\u306f<strong>\u816b\u760d\u306e\u8840\u6d41<\/strong>\u3068<strong>\u9178\u7d20\u5316<\/strong>\u3092\u6539\u5584\u3057\u3001\u816b\u760d\u306e\u4f4e\u9178\u7d20\u72b6\u614b\u3092\u9006\u8ee2\u3055\u305b\u307e\u3059\u3002\u5341\u5206\u306b\u9178\u7d20\u5316\u3055\u308c\u305f\u816b\u760d\u7d30\u80de\u306f\u3001<strong>\u5316\u5b66\u7642\u6cd5<\/strong>\uff08CT\uff09\u3084<strong>\u653e\u5c04\u7dda\u7642\u6cd5<\/strong>\uff08RT\uff09\u306b\u3088\u308b\u7834\u58ca\u306b\u5bfe\u3057\u3066\u6709\u610f\u306b\u611f\u53d7\u6027\u304c\u9ad8\u307e\u308b\u305f\u3081\u3001\u3053\u308c\u306f\u4e0d\u53ef\u6b20\u306a\u8981\u7d20\u3067\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[9, 41]<\/span>\u3002<\/li>\n\u00a0\t<li style=\"margin-bottom: 15px; text-align: left;\"><strong>\u5316\u5b66\/\u653e\u5c04\u7dda\u7642\u6cd5\u306e\u6709\u52b9\u6027\uff1a<\/strong> \u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u306f<strong>\u5316\u5b66\u304a\u3088\u3073\u653e\u5c04\u7dda\u306e<strong style=\"color: #d32f2f;\">\u611f\u53d7\u6027\u5897\u611f\u5264<\/strong><\/strong>\u3068\u3057\u3066\u4f5c\u7528\u3057\u3001\u816b\u760d\u3078\u306e\u9178\u7d20\u4f9b\u7d66\u3092\u6539\u5584\uff08<em>\u653e\u5c04\u7dda\u5897\u611f\u52b9\u679c<\/em>\uff09\u3055\u305b\u308b\u3068\u3068\u3082\u306b\u3001\u30b7\u30b9\u30d7\u30e9\u30c1\u30f3\u3001\u30b2\u30e0\u30b7\u30bf\u30d3\u30f3\u3001\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3\u306a\u3069\u306e\u85ac\u5264\u306e\u52b9\u679c\u3092\u5411\u4e0a\u3055\u305b\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[12, 16, 36]<\/span>\u3002<\/li>\n<\/ul>\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3119e45 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"3119e45\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n<h3 style=\"text-align: left; color: #2c3e50; border-bottom: 2px solid #eef2f6; padding-bottom: 10px; margin-top: 30px;\">B. \u5f37\u529b\u306a\u6297\u816b\u760d\u514d\u75ab\u5fdc\u7b54\u306e\u8a98\u5c0e\uff08\u514d\u75ab\u8abf\u7bc0\uff09<\/h3>\n<p style=\"text-align: left;\">WBH\u306f\u8eab\u4f53\u306e\u9632\u5fa1\u30b7\u30b9\u30c6\u30e0\u306e\u5f37\u529b\u306a\u6d3b\u6027\u5316\u56e0\u5b50\u3067\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[11]<\/span>\uff1a<\/p>\n\n<ul style=\"padding-left: 20px; list-style-type: square;\">\n\u00a0\t<li style=\"margin-bottom: 15px; text-align: left;\"><strong>\u71b1\u30b7\u30e7\u30c3\u30af\u30bf\u30f3\u30d1\u30af\u8cea\uff08HSPs\uff09\uff1a<\/strong> \u71b1\u30b9\u30c8\u30ec\u30b9\u306f<strong>HSP70<\/strong>\u306e\u5408\u6210\u3068\u653e\u51fa\u3092\u523a\u6fc0\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u300c\u5371\u967a\u4fe1\u53f7\u300d\u3068\u3057\u3066\u4f5c\u7528\u3057\u3001\u514d\u75ab\u7cfb\u306e<strong>\u7d30\u80de\u50b7\u5bb3\u6027T\u30ea\u30f3\u30d1\u7403\uff08CTL\uff09<\/strong>\u306b\u3088\u308b\u653b\u6483\u3092\u5f37\u5316\u3059\u308b\u305f\u3081\u306b\u304c\u3093\u7d30\u80de\u3092\u6a19\u8b58\u3057\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[9, 10, 29]<\/span>\u3002<\/li>\n\u00a0\t<li style=\"margin-bottom: 15px; text-align: left;\"><strong>\u4e3b\u8981\u306a\u514d\u75ab\u7d30\u80de\u306e\u6d3b\u6027\u5316\uff1a<\/strong> 39\uff5e43\u00b0C\u306e\u6e29\u5ea6\u7bc4\u56f2\u306f\u3001<strong>\u30ca\u30c1\u30e5\u30e9\u30eb\u30ad\u30e9\u30fc\uff08NK\uff09\u7d30\u80de<\/strong>\u306e\u6d3b\u6027\u3092\u9ad8\u3081\u3001<strong>\u30d8\u30eb\u30d1\u30fcT\u7d30\u80de\u3001\u7d30\u80de\u50b7\u5bb3\u6027T\u7d30\u80de\u3001\u6a39\u72b6\u7d30\u80de\u3001\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8<\/strong>\u306e\u6d3b\u52d5\u3092\u4fc3\u9032\u3059\u308b\u4e00\u65b9\u3067\u3001<span style=\"text-decoration: underline;\">\u514d\u75ab\u6291\u5236\u7d30\u80de\u3092\u5f31\u4f53\u5316\u3055\u305b\u308b\u53ef\u80fd\u6027<\/span>\u304c\u3042\u308a\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[9, 10, 11, 25, 26]<\/span>\u3002<\/li>\n\u00a0\t<li style=\"margin-bottom: 15px; text-align: left;\"><strong>T\u30ea\u30f3\u30d1\u7403\u306e\u5897\u52a0\uff1a<\/strong> \u767a\u71b1\u57dfWBH\uff08FR-WBH\uff09\u306f\u3001\u30ea\u30f3\u30d1\u5668\u5b98\u306b\u304a\u3051\u308b<strong>\u7d30\u80de\u50b7\u5bb3\u6027T\u30ea\u30f3\u30d1\u7403\u306e\u6570\u3092\u6709\u610f\u306b\u5897\u52a0\uff08\u4f8b\uff1a3\u500d\uff09<\/strong>\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u3001\u3053\u308c\u306b\u3088\u308a<strong>\u5168\u8eab\u7684\u306a\u6297\u816b\u760d\u514d\u75ab\u653b\u6483\u3092\u5f37\u5316<\/strong>\u3057\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[10]<\/span>\u3002<\/li>\n\u00a0\t<li style=\"margin-bottom: 15px; text-align: left;\"><strong>\u30ef\u30af\u30c1\u30f3\u3068\u6297\u539f\u63d0\u793a\u7d30\u80de\uff08APCs\uff09\uff1a<\/strong> \u5168\u8eab\u6e29\u71b1\u7642\u6cd5\uff08WHT\uff09\u306f\u6297\u539f\u63d0\u793a\u7d30\u80de\uff08APC\uff09\u306e\u6a5f\u80fd\u3092\u8abf\u7bc0\u3057\u3001HSP110\u3084GRP170\u306b\u57fa\u3065\u304f\u3082\u306e\u3092\u542b\u3080\u304c\u3093\u30ef\u30af\u30c1\u30f3\u306e\u6709\u52b9\u6027\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[37, 28]<\/span>\u3002<\/li>\n<\/ul>\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bbbd880 animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"bbbd880\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e99507b elementor-widget elementor-widget-heading\" data-id=\"e99507b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">4. \u81e8\u5e8a\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u96c6\u5b66\u7684\u6cbb\u7642\u306b\u304a\u3051\u308b\u76f8\u4e57\u52b9\u679c<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e6a66ba animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"e6a66ba\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\"> <h3 style=\"text-align: left; color: #2c3e50; border-bottom: 2px solid #eef2f6; padding-bottom: 10px; margin-top: 30px;\">A. \u514d\u75ab\u7642\u6cd5\uff08\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264 &#8211; ICI\uff09\u3068\u306e\u76f8\u4e57\u52b9\u679c<\/h3> <p style=\"text-align: left;\">131\u540d\u306e\u9032\u884c\uff08\u30b9\u30c6\u30fc\u30b8IV\uff09\u304c\u3093\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30ec\u30c8\u30ed\u30b9\u30da\u30af\u30c6\u30a3\u30d6\u306a\u75c7\u4f8b\u30b7\u30ea\u30fc\u30ba\u306b\u304a\u3044\u3066\u3001\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\uff08\u30a4\u30d4\u30ea\u30e0\u30de\u30d6\u3001\u30cb\u30dc\u30eb\u30de\u30d6\uff09\u304a\u3088\u3073IL-2\u3068\u3068\u3082\u306b\u3001<strong>\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2<\/strong>\u3092\u542b\u3080\u96c6\u5b66\u7684\u30d7\u30ed\u30c8\u30b3\u30eb\u304c\u8abf\u67fb\u3055\u308c\u307e\u3057\u305f <span style=\"color: #6a6a6a; font-size: 0.9em;\">[18]<\/span>\u3002<\/p>\n\n<div style=\"background: #f0f7ff; padding: 25px; border-radius: 12px; border-left: 5px solid #007bff; margin: 25px 0;\"> <p style=\"text-align: left; margin: 0; font-size: 1.05em;\"><strong style=\"color: #0056b3;\">\u4e3b\u306a\u7d50\u8ad6\uff1a<\/strong> wIRA\u3092\u7528\u3044\u305f\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u306f\u3001<strong>\u6297\u816b\u760d\u514d\u75ab\u5fdc\u7b54\u3092\u6700\u5927\u5316<\/strong>\u3059\u308b\u305f\u3081\u306e<strong>\u4e0d\u53ef\u6b20\u304b\u3064\u4e0d\u53ef\u6b20\u306a\u69cb\u6210\u8981\u7d20<\/strong>\u3067\u3042\u308b\u3068\u5224\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p> <p style=\"text-align: left; margin-top: 15px; margin-bottom: 0;\"><strong>WBH\u306fT\u7d30\u80de\u3092\u6d3b\u6027\u5316\u30fb\u52d5\u54e1\u3057<\/strong>\uff08HSP70\u306e\u8a98\u5c0e\u3068\u816b\u760d\u6297\u539f\u306e\u653e\u51fa\u306b\u3088\u308b\uff09\u3001\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\u304c\u3053\u308c\u3089\u306e\u4e8b\u524d\u6d3b\u6027\u5316\u3055\u308c\u305fT\u7d30\u80de\u306e\u300c\u30d6\u30ec\u30fc\u30ad\u3092\u5916\u3059\u300d\u3053\u3068\u3067\u3001\u9032\u884c\u75be\u60a3\u306b\u304a\u3044\u3066\u7570\u4f8b\u306b\u9ad8\u3044\u826f\u597d\u306a\u81e8\u5e8a\u53cd\u5fdc\u7387\u3092\u3082\u305f\u3089\u3057\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[18]<\/span>\u3002<\/p>\n\n<\/div> <\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-464662f animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"464662f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n<h3 style=\"text-align: left; color: #2c3e50; border-bottom: 2px solid #eef2f6; padding-bottom: 10px; margin-top: 30px;\">B. \u69d8\u3005\u306a\u304c\u3093\u306b\u304a\u3051\u308b\u81e8\u5e8a\u5fdc\u7528<\/h3>\n<ul style=\"padding-left: 20px; list-style-type: none;\">\n\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #007bff; padding-left: 15px;\"><strong style=\"color: #007bff;\">\u81b5\u81d3\u304c\u3093\uff1a<\/strong> \u5316\u5b66\u7642\u6cd5\u304a\u3088\u3073\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u03b1\u3068\u7d44\u307f\u5408\u308f\u305b\u305f\u8efd\u5ea6WBH\uff08FR-WBH\uff09\u3092\u7528\u3044\u305f\u7b2cI-II\u76f8\u30d7\u30ed\u30c8\u30b3\u30eb\u3067\u306f\u3001<strong>\u6cbb\u7642\u62b5\u6297\u6027\u306e\u60a3\u8005\u306e\u7d04\u534a\u6570\u306b\u304a\u3044\u3066\u5c11\u306a\u304f\u3068\u308250%\u306e\u816b\u760d\u9000\u7e2e<\/strong>\u304c\u793a\u3055\u308c\u307e\u3057\u305f <span style=\"color: #6a6a6a; font-size: 0.9em;\">[4, 22]<\/span>\u3002<\/li>\n\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #007bff; padding-left: 15px;\"><strong style=\"color: #007bff;\">\u4e73\u304c\u3093\uff08\u518d\u767a\uff09\uff1a<\/strong> \u518d\u7167\u5c04\u307e\u305f\u306f\u653e\u5c04\u7dda\u7642\u6cd5\u3068\u7d44\u307f\u5408\u308f\u305b\u305f\u5168\u8eab\u6e29\u71b1\u7642\u6cd5\uff08WHT\uff09\u306f\u3001\u5c40\u6240\u9032\u884c\u4e73\u304c\u3093\u304a\u3088\u3073\u80f8\u58c1\u518d\u767a\u306b\u5bfe\u3057\u3066\u6709\u52b9\u6027\u3092\u793a\u3057\u3066\u304a\u308a\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u30c7\u30fc\u30bf\u306b\u3088\u3063\u3066\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[39, 40]<\/span>\u3002<\/li>\n\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #007bff; padding-left: 15px;\"><strong style=\"color: #007bff;\">\u5375\u5de3\u304c\u3093\uff1a<\/strong> <strong>\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3<\/strong>\u3068\u4f75\u7528\u3057\u305fWBH\u306f\u3001\u518d\u767a\u5375\u5de3\u304c\u3093\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7b2cII\u76f8\u8a66\u9a13\u3067\u8abf\u67fb\u3055\u308c\u307e\u3057\u305f <span style=\"color: #6a6a6a; font-size: 0.9em;\">[16, 20]<\/span>\u3002<\/li>\n\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #007bff; padding-left: 15px;\"><strong style=\"color: #007bff;\">\u5927\u8178\u304c\u3093\uff1a<\/strong> wIRA\u3092\u7528\u3044\u305fWBH\u306f\u3001\u7b2cI\/II\u76f8\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001\u30d5\u30a9\u30f3\u30fb\u30a2\u30eb\u30c7\u30f3\u30cc\u306e\u5168\u8eab\u304c\u3093\u591a\u6bb5\u968e\u7642\u6cd5\uff08sCMT\uff09\u306e\u6587\u8108\u3067\u5316\u5b66\u7642\u6cd5\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u4f7f\u7528\u3055\u308c\u307e\u3057\u305f <span style=\"color: #6a6a6a; font-size: 0.9em;\">[15]<\/span>\u3002<\/li>\n<\/ul>\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4cb34f6 e-con-full animated-slow e-flex elementor-invisible e-con e-child\" data-id=\"4cb34f6\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c7ca566 elementor-widget elementor-widget-heading\" data-id=\"c7ca566\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">5. \u8fc5\u901f\u306a\u75bc\u75db\u7de9\u548c\u3068QOL\uff08\u751f\u6d3b\u306e\u8cea\uff09\u306e\u6709\u610f\u306a\u5411\u4e0a<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8ec3c40 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"8ec3c40\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n<p style=\"font-size: 1.1em; text-align: left;\">Bull\u535a\u58eb\u306e\u7814\u7a76 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[12]<\/span> \u3084\u3001\u7279\u306bSahinbas\u3089\u306b\u3088\u3063\u3066\u884c\u308f\u308c\u305f\u6700\u8fd1\u306e<strong>\u7b2cIII\u76f8\u81e8\u5e8a\u8a66\u9a13<\/strong> <span style=\"color: #6a6a6a; font-size: 0.9em;\">[14]<\/span> \u3067\u89b3\u5bdf\u3055\u308c\u3066\u3044\u308b\u3088\u3046\u306b\u3001\u60a3\u8005\u306f<strong>\u8fc5\u901f\u306a\u75bc\u75db\u7de9\u548c<\/strong>\u3068\u5168\u822c\u7684\u306a\u5e78\u798f\u611f\u306e\u5411\u4e0a\u3092\u5b9f\u611f\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n<div style=\"background: #fff9e6; padding: 20px; border-radius: 10px; border-left: 5px solid #ffcc00; margin: 25px 0;\">\n<p style=\"margin: 0; color: #856404; font-weight: bold;\"><i class=\"fa fa-info-circle\"><\/i> \u81e8\u5e8a\u7684\u77e5\u898b\uff1a<\/p>\n<p style=\"margin-top: 10px; margin-bottom: 0; font-style: italic;\">wIRA\u7642\u6cd5\u306f\u3001\u816b\u760d\u306e\u5236\u5fa1\u306b\u5bc4\u4e0e\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u93ae\u75db\u5264\u306e\u5fc5\u8981\u6027\u3092\u5927\u5e45\u306b\u6e1b\u5c11\u3055\u305b\u3001\u9032\u884c\u764c\u306e\u60a3\u8005\u3067\u3042\u3063\u3066\u3082\u53ef\u52d5\u6027\u3068\u6d3b\u529b\u3092\u56de\u5fa9\u3055\u305b\u307e\u3059\u3002<\/p>\n\n<\/div>\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cfebbf0 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"cfebbf0\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n<h3 style=\"text-align: left; color: #d32f2f; border-bottom: 2px solid #f2f2f2; padding-bottom: 10px;\">\u9aa8\u8ee2\u79fb\u306b\u5bfe\u3059\u308b\u7b2cIII\u76f8\u81e8\u5e8a\u8a66\u9a13\uff082024\u5e74\uff09<\/h3>\n<p style=\"text-align: left;\">2024\u5e74\u3001<a style=\"color: #007bff;\" href=\"[https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0306456524000226](https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0306456524000226)\" target=\"_blank\" rel=\"noopener\">Sahinbas\u3089\u306f\u3001\u4e3b\u306b\u4e73\u304c\u3093\u3068\u524d\u7acb\u817a\u304c\u3093\u306b\u3088\u308b\u9aa8\u8ee2\u79fb\u306e\u75db\u307f\u306b\u5bfe\u3057<\/a>\u3001\u653e\u5c04\u7dda\u7642\u6cd5\uff08RT\uff09\u306b\u52a0\u3048\u3066WBH wIRA Iratherm\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u88c5\u7f6e\u3092\u7528\u3044\u305f\u7b2cIII\u76f8\u8a66\u9a13\u306e\u7d50\u679c\u3092\u516c\u8868\u3057\u307e\u3057\u305f <span style=\"color: #6a6a6a; font-size: 0.9em;\">[14]<\/span>\u3002<\/p>\n\n<div style=\"background: #fdfdfd; padding: 20px; border: 1px solid #e0e0e0; border-radius: 8px; margin: 20px 0;\">\n\n<strong>\u4e3b\u306a\u77e5\u898b\uff1a<\/strong> \u653e\u5c04\u7dda\u7642\u6cd5\uff08RT\uff09\u5358\u72ec\u7fa4\u3067\u306f\u75db\u307f\u304c\u6700\u3082\u6fc0\u3057\u304f\u6301\u7d9a\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306b\u5bfe\u3057\u3001<strong>RT + WBH<\/strong>\u7fa4\u3067\u306f\u3001\u6cbb\u7642\u5f8c2\u30f6\u6708\u4ee5\u5185\u306e<strong>\u5b8c\u5168\u594f\u52b9\u7387\uff08CR\uff09\u304c47.4%<\/strong>\u306b\u9054\u3057\u3001RT\u5358\u72ec\u7fa4\u306e5.3%\u3092\u5927\u304d\u304f\u4e0a\u56de\u308a\u307e\u3057\u305f\u3002\n\n<strong>\u75db\u307f\u304c\u5b8c\u5168\u306b\u6d88\u5931\u3059\u308b\u307e\u3067\u306e\u671f\u9593\u306f\u3001RT + WBH\u7fa4\u3067\u308f\u305a\u304b10\u65e5<\/strong>\u3067\u3042\u3063\u305f\u306e\u306b\u5bfe\u3057\u3001RT\u5358\u72ec\u7fa4\u3067\u306f\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\uff08\u5b8c\u5168\u6d88\u5931\uff09\u306b\u9054\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\n\n<\/div>\n<div style=\"overflow-x: auto; margin-top: 25px;\">\n<table style=\"width: 100%; border-collapse: collapse; text-align: left; border: 1px solid #ddd;\">\n<thead>\n<tr style=\"background-color: #007bff; color: white;\">\n<th style=\"padding: 12px; border: 1px solid #ddd;\">QoL\u6307\u6a19 \/ \u75bc\u75db\u6539\u5584<\/th>\n<th style=\"padding: 12px; border: 1px solid #ddd;\">RT \u5358\u72ec\u7642\u6cd5<\/th>\n<th style=\"padding: 12px; border: 1px solid #ddd;\">RT + \u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2 (wIRA)<\/th>\n<th style=\"padding: 12px; border: 1px solid #ddd;\">QoL\u3078\u306e\u5f71\u97ff<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 12px; border: 1px solid #ddd;\"><strong>\u5b8c\u5168\u594f\u52b9\u7387 (CR)<\/strong> (2\u30f6\u6708\u6642\u70b9)<\/td>\n<td style=\"padding: 12px; border: 1px solid #ddd;\">5.3 %<\/td>\n<td style=\"padding: 12px; border: 1px solid #ddd; background: #eef9ee;\"><strong>47.4 %<\/strong><\/td>\n<td style=\"padding: 12px; border: 1px solid #ddd; color: #28a745;\">\u75db\u307f\u304c\u5b8c\u5168\u306b\u6d88\u5931\u3059\u308b\u78ba\u7387\u304c <strong>+894% \u5411\u4e0a<\/strong><\/td>\n<\/tr>\n<tr style=\"background-color: #f9f9f9;\">\n<td style=\"padding: 12px; border: 1px solid #ddd;\"><strong>\u75db\u307f\u304c\u5b8c\u5168\u306b\u6d88\u5931\u3059\u308b\u307e\u3067\u306e\u671f\u9593<\/strong><\/td>\n<td style=\"padding: 12px; border: 1px solid #ddd;\">\u672a\u5230\u9054<\/td>\n<td style=\"padding: 12px; border: 1px solid #ddd;\"><strong>10\u65e5<\/strong><\/td>\n<td style=\"padding: 12px; border: 1px solid #ddd;\">\u300c\u6709\u610f\u304b\u3064\u8fc5\u901f\u306a\u300d\u30e1\u30ea\u30c3\u30c8<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 12px; border: 1px solid #ddd;\"><strong>\u75bc\u75db\u7de9\u548c\u306e\u6301\u7d9a\u671f\u9593<\/strong><\/td>\n<td style=\"padding: 12px; border: 1px solid #ddd;\">\u4e2d\u592e\u5024\uff1a28\u65e5<\/td>\n<td style=\"padding: 12px; border: 1px solid #ddd;\">\u4e2d\u592e\u5024\uff1a24\u9031\u9593\u4ee5\u4e0a<\/td>\n<td style=\"padding: 12px; border: 1px solid #ddd;\">\u7de9\u548c\u671f\u9593\u304c <strong>6\u500d\u306b\u5ef6\u9577<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e97cd55 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"e97cd55\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n<p style=\"text-align: left;\">RF\uff08\u9ad8\u5468\u6ce2\uff09\u5c40\u6240\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u3092\u7528\u3044\u305f\u540c\u69d8\u306e<a style=\"color: #007bff;\" title=\"Phase III Chi MS et al. 2017 Study\" href=\"[https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360-3016(17)33930-5](https:\/\/www.google.com\/url?sa=E&#038;source=gmail&#038;q=https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360-3016(17)33930-5)\" target=\"_blank\" rel=\"noopener\">Chi MS\u3089\u306b\u3088\u308b\u7b2cIII\u76f8\u8a66\u9a13\uff082017\u5e74\uff09<\/a>\u3068\u6bd4\u8f03\u3057\u3066\u3082\u3001<strong>WBH wIRA\uff08\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff09<\/strong>\u3092\u7528\u3044\u3066\u5f97\u3089\u308c\u305f\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u306f\u9065\u304b\u306b\u512a\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<p style=\"text-align: left; font-style: italic; color: #666; margin-bottom: 10px;\">RF HT + RT \u8a66\u9a13\u7d50\u679c\uff08\u5c40\u6240\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff09\uff1a<\/p>\n\n<div style=\"overflow-x: auto; margin-bottom: 30px;\">\n<table style=\"width: 100%; border-collapse: collapse; text-align: left; border: 1px solid #ddd; font-size: 14px;\">\n<thead>\n<tr style=\"background-color: #6c757d; color: white;\">\n<th style=\"padding: 10px; border: 1px solid #ddd;\">QoL\u6307\u6a19 \/ \u75bc\u75db\u6539\u5584<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd;\">RT \u5358\u72ec\u7642\u6cd5<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd;\">RT + \u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2 (RF HT)<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd;\">QoL\u3078\u306e\u5f71\u97ff<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u5b8c\u5168\u594f\u52b9\u7387 (CR)<\/strong> (3\u30f6\u6708\u6642\u70b9)<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">7.1 %<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">37.9 %<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u75db\u307f\u304c\u5b8c\u5168\u306b\u6d88\u5931\u3059\u308b\u78ba\u7387\u304c 533% \u5411\u4e0a<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u75bc\u75db\u7de9\u548c\u306e\u6301\u7d9a\u671f\u9593<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u4e2d\u592e\u5024\uff1a55\u65e5<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u4e2d\u592e\u5024\uff1a24\u9031\u9593\u6642\u70b9\u3067\u672a\u5230\u9054<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u7de9\u548c\u671f\u9593\u304c 3\u500d\u306b\u5ef6\u9577<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div style=\"background: #2c3e50; color: #ffffff; padding: 30px; border-radius: 15px; margin-top: 40px; box-shadow: 0 4px 15px rgba(0,0,0,0.1);\">\n<h4 style=\"color: #007bff; margin-top: 0; text-transform: uppercase; letter-spacing: 1px;\">\u8981\u7d04\u3068\u7d50\u8ad6<\/h4>\n<p style=\"font-size: 1.1em; margin-bottom: 0;\">wIRA\u6280\u8853\u306e\u57fa\u790e\u7814\u7a76\u304b\u3089\u6975\u3081\u3066\u91cd\u8981\u306a\u7b2cIII\u76f8\u81e8\u5e8a\u8a66\u9a13\u306b\u81f3\u308b\u307e\u3067\u306e\u7d71\u5408\u3055\u308c\u305f\u79d1\u5b66\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u3001\u816b\u760d\u5b66\u306b\u304a\u3051\u308b<strong>\u591a\u89d2\u7684\u5f71\u97ff\u3092\u6301\u3064\u88dc\u52a9\u7642\u6cd5<\/strong>\u3068\u3057\u3066\u306e\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08WBH\uff09\u306e\u5f79\u5272\u3092\u88cf\u4ed8\u3051\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u306f\u3001<strong>\u5316\u5b66\u7642\u6cd5\u30fb\u653e\u5c04\u7dda\u7642\u6cd5\u306e\u52b9\u679c\u3092\u9ad8\u3081\u3001\u5168\u8eab\u306e\u514d\u75ab\u7cfb\u3092\u6d3b\u6027\u5316\uff08\u514d\u75ab\u7642\u6cd5\u3068\u306e\u76f8\u4e57\u52b9\u679c\u3092\u542b\u3080\uff09\u3055\u305b\u3001\u304c\u3093\u60a3\u8005\u306e\u75bc\u75db\u7ba1\u7406\u3068QOL\u3092\u5287\u7684\u306b\u6539\u5584<\/strong>\u3057\u307e\u3059\u3002<\/p>\n\n<\/div>\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2b9b952 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"2b9b952\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9003cfd elementor-widget elementor-widget-heading\" data-id=\"9003cfd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">6. \u5168\u8eab\u7684\u306a\u751f\u7406\u5b66\u7684\u5229\u70b9\u3068\u4ed6\u306e\u75be\u60a3\u306b\u304a\u3051\u308b\u6cbb\u7642\u306e\u53ef\u80fd\u6027<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0307397 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"0307397\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n<p style=\"font-size: 1.15em; color: #2c3e50; background: #f8f9fa; padding: 20px; border-radius: 10px; border-right: 4px solid #28a745; text-align: left;\"><strong>wIRA\u653e\u5c04<\/strong>\u3092\u7528\u3044\u305f\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08WBH\uff09\u306b\u3088\u308b\u7a4f\u3084\u304b\u3067\u5236\u5fa1\u3055\u308c\u305f\u52a0\u71b1\u306f\u3001\u8907\u96d1\u306a\u4f53\u6e29\u8abf\u7bc0\u53cd\u5fdc\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001<strong>\u5e83\u7bc4\u306a\u5168\u8eab\u7684\u30e1\u30ea\u30c3\u30c8<\/strong>\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u816b\u760d\u5b66\u306b\u3068\u3069\u307e\u3089\u306a\u3044\u6cbb\u7642\u306e\u53ef\u80fd\u6027\u304c\u5e83\u304c\u308a\u307e\u3059\uff1a<\/p>\n\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f8b16cd animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"f8b16cd\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\"><h3 style=\"text-align: left; color: #2c3e50; border-bottom: 2px solid #eef2f6; padding-bottom: 10px; margin-top: 30px;\">A. \u7b4b\u9aa8\u683c\u7cfb\u304a\u3088\u3073\u75bc\u75db\u7ba1\u7406<\/h3><p style=\"text-align: left;\">WBH\u306f\u3001\u7b4b\u7dca\u5f35\u3084\u5fae\u5c0f\u5faa\u74b0\u3078\u306e\u751f\u7406\u5b66\u7684\u52b9\u679c\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u6162\u6027\u75bc\u75db\u5019\u7fa4\u306e\u7ba1\u7406\u306b\u52b9\u679c\u7684\u3067\u3059\uff1a<\/p><ul style=\"padding-left: 20px; list-style-type: none;\">\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #28a745; padding-left: 15px;\"><strong>\u80cc\u90e8\u75db\uff08\u6162\u6027\u8170\u75db\uff09\uff1a<\/strong> \u7814\u7a76\u306b\u3088\u308a\u3001\u8efd\u5ea6\u306eWBH\u3092\u5b9a\u5e38\u7684\u306a\u96c6\u4e2d\u7684\u75bc\u75db\u6cbb\u7642\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u6162\u6027\u306e\u975e\u7279\u7570\u7684\u8170\u75db\u60a3\u8005\u306b\u5927\u304d\u306a\u5229\u76ca\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[53, 54]<\/span>\u3002<\/li>\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #28a745; padding-left: 15px;\"><strong>\u7dda\u7dad\u7b4b\u75db\u75c7\u5019\u7fa4\uff08FMS\uff09\uff1a<\/strong> WBH\u306fFMS\u306e\u88dc\u52a9\u7684\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u5b9f\u8a3c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306b\u3088\u308a\u3001\u8efd\u5ea6\u306ewIRA WBH\u306e\u6709\u52b9\u6027\u304c\u5b9f\u8a3c\u3055\u308c\u3001<strong>\u75bc\u75db\u5f37\u5ea6<\/strong>\u3084<strong>\u7cbe\u795e\u72b6\u614b<\/strong>\u3078\u306e\u5f71\u97ff\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[17, 56, 57]<\/span>\u3002<\/li>\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #28a745; padding-left: 15px;\"><strong>\u5f37\u76f4\u6027\u810a\u690e\u708e\uff08AS\uff09\uff1a<\/strong> WBH\u306fAS\u60a3\u8005\u306b\u304a\u3044\u3066\u514d\u75ab\u8abf\u7bc0\u52b9\u679c\u3092\u793a\u3057\u3066\u304a\u308a\u3001<strong>\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3-10\uff08IL-10\uff09<\/strong>\u306e\u3088\u3046\u306a\u6297\u708e\u75c7\u30e1\u30c7\u30a3\u30a8\u30fc\u30bf\u30fc\u3092\u5897\u52a0\u3055\u305b\u3001TNF-$\u03b1$\u306e\u3088\u3046\u306a\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3092\u8abf\u7bc0\u3057\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[58, 59, 52]<\/span>\u3002<\/li>\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #28a745; padding-left: 15px;\"><strong>\u5168\u8eab\u6027\u5f37\u76ae\u75c7\u306b\u304a\u3051\u308b\u30ec\u30a4\u30ce\u30fc\u73fe\u8c61\uff1a<\/strong> \u8d64\u5916\u7dda\u306b\u3088\u308b\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u306f\u8840\u7ba1\u53ce\u7e2e\u75c7\u72b6\u306e\u6cbb\u7642\u306b\u52b9\u679c\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u304a\u308a\u3001\u660e\u78ba\u306a\u8840\u7ba1\u3078\u306e\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[49]<\/span>\u3002<\/li><\/ul><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b0c1b89 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"b0c1b89\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\"> <h3 style=\"text-align: left; color: #c0392b; border-bottom: 2px solid #f8d7da; padding-bottom: 10px; margin-top: 30px;\">B. \u5fc3\u8840\u7ba1\u304a\u3088\u3073\u5faa\u74b0\u5668\u7cfb\u306e\u5065\u5eb7 \u2764\ufe0f<\/h3> <p style=\"text-align: left;\">\u816b\u760d\u3078\u306e\u8840\u6d41\u6539\u5584\u306b\u3068\u3069\u307e\u3089\u305a\u3001WBH\u306f\u5faa\u74b0\u5668\u7cfb\u306b\u5bfe\u3057\u3066\u3082\u7279\u6709\u306e\u52b9\u679c\u3092\u3082\u305f\u3089\u3057\u307e\u3059\uff1a<\/p>\n\n<ul style=\"padding-left: 20px; list-style-type: none;\"> \u00a0 <li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #c0392b; padding-left: 15px;\"><strong>\u672c\u614b\u6027\u9ad8\u8840\u5727\u75c7\uff1a<\/strong> \u4e00\u9023\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u9ad8\u8840\u5727\u60a3\u8005\uff08WHO\u5206\u985e\u30b9\u30c6\u30fc\u30b8I\u304a\u3088\u3073II\uff09\u306b\u5bfe\u3059\u308b\u8efd\u5ea6IR-A\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u306e\u4f7f\u7528\u304c\u8abf\u67fb\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u7d99\u7d9a\u7684\u306a\u6cbb\u7642\u304c<strong>\u4e2d\u5fc3\u7684\u304a\u3088\u3073\u672b\u68a2\u7684\u306a\u8108\u6ce2<\/strong>\u3001\u8840\u5727\u3001\u3055\u3089\u306b<strong>\u8840\u6db2\u7c98\u5ea6<\/strong>\u306b\u5bfe\u3057\u3066\u597d\u307e\u3057\u3044\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3001\u975e\u85ac\u7269\u7684\u306a\u7406\u5b66\u7642\u6cd5\u306e\u9078\u629e\u80a2\u3068\u3057\u3066\u306eWBH\u306e\u5f79\u5272\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f <span style=\"color: #6a6a6a; font-size: 0.9em;\">[44, 47]<\/span>\u3002<\/li> <\/ul> <\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ce4fdb9 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"ce4fdb9\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\"><h3 style=\"text-align: left; color: #673ab7; border-bottom: 2px solid #ede7f6; padding-bottom: 10px; margin-top: 30px;\">C. \u795e\u7d4c\u5185\u5206\u6ccc\u304a\u3088\u3073\u5fc3\u7406\u5b66\u7684\u52b9\u679c<\/h3><p style=\"text-align: left;\">WBH\u306f\u8eab\u4f53\u306e\u795e\u7d4c\u5185\u5206\u6ccc\u7cfb\u306b\u50cd\u304d\u304b\u3051\u3001\u6c17\u5206\u3084\u4ee3\u8b1d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\uff1a<\/p><ul style=\"padding-left: 20px; list-style-type: none;\">\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #673ab7; padding-left: 15px;\"><strong>\u5927\u3046\u3064\u75c5\u6027\u969c\u5bb3\uff08MDD\uff09\uff1a<\/strong> \u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001\u5358\u56de\u306eWBH\u30bb\u30c3\u30b7\u30e7\u30f3\u304c\u901f\u52b9\u6027\u306e\u6297\u3046\u3064\u85ac\u306e\u3088\u3046\u306b\u4f5c\u7528\u3057\u3001\u6570\u9031\u9593\u306b\u308f\u305f\u3063\u3066\u6291\u3046\u3064\u75c7\u72b6\u3092\u8efd\u6e1b\u3055\u305b\u308b\u3053\u3068\u304c\u5b9f\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u52b9\u679c\u306f\u3001\u71b1\u306b\u3088\u308b\u514d\u75ab\u7cfb\u304a\u3088\u3073\u708e\u75c7\u7d4c\u8def\u306e\u6d3b\u6027\u5316\u304c\u8133\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[51]<\/span>\u3002<\/li>\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #673ab7; padding-left: 15px;\"><strong>\u30db\u30eb\u30e2\u30f3\u8abf\u7bc0\uff08\u5185\u5206\u6ccc\u5b66\uff09\uff1a<\/strong> WBH\u306f<strong>\u8996\u5e8a\u4e0b\u90e8-\u4e0b\u5782\u4f53-\u526f\u814e\uff08HPA\uff09\u8ef8<\/strong>\u3092\u523a\u6fc0\u3057\u3001\u30db\u30eb\u30e2\u30f3\u30ec\u30d9\u30eb\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u4e2d\u306e<strong>\u6210\u9577\u30db\u30eb\u30e2\u30f3<\/strong>\u3084<strong>\u30d7\u30ed\u30e9\u30af\u30c1\u30f3<\/strong>\u306e\u53cd\u5fdc\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u5185\u5206\u6ccc\u8abf\u7bc0\u3078\u306e\u5f71\u97ff\u304c\u6d6e\u304d\u5f6b\u308a\u306b\u306a\u3063\u3066\u3044\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[42, 43]<\/span>\u3002<\/li>\u00a0\t<li style=\"margin-bottom: 18px; text-align: left; border-left: 3px solid #673ab7; padding-left: 15px;\"><strong>\u4ee3\u8b1d\u3068\u7d30\u80de\u53cd\u5fdc\uff1a<\/strong> WBH\u306f\u57fa\u790e\u4ee3\u8b1d\u7387\u3092\u52a0\u901f\u3055\u305b\u307e\u3059\u3002\u7d30\u80de\u30ec\u30d9\u30eb\u3067\u306f\u3001\u71b1\u306f$pO_2$\uff08\u9178\u7d20\u5206\u5727\uff09\u52d5\u614b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u76ae\u819a\u306b\u304a\u3051\u308b<strong>\u30d5\u30a7\u30ea\u30c1\u30f3<\/strong>\u306e\u3088\u3046\u306a\u4fdd\u8b77\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5408\u6210\u306b\u95a2\u4e0e\u3057\u3001\u7d44\u7e54\u306e\u4fee\u5fa9\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u307e\u3059 <span style=\"color: #6a6a6a; font-size: 0.9em;\">[48, 46]<\/span>\u3002<\/li><\/ul><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-91f7153 elementor-invisible elementor-widget elementor-widget-image\" data-id=\"91f7153\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;zoomIn&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/ardenneiratherm.com\/wp-content\/uploads\/2025\/10\/von-Ardenne-Iratherm-10000-WBH-wIRA-hyperthermia-device-summary.jpg\" title=\"\" alt=\"von Ardenne Iratherm 10000 WBH wIRA hyperthermia-device-summary\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ae37e3c e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"ae37e3c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a7dda12 elementor-widget elementor-widget-heading\" data-id=\"a7dda12\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u63a8\u5968\u3055\u308c\u308b\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08WBH\uff09\u306e\u30bb\u30c3\u30b7\u30e7\u30f3\u56de\u6570\u3068\u76ee\u6a19\u6e29\u5ea6\u306b\u95a2\u3059\u308b\u3088\u304f\u3042\u308b\u8cea\u554f\uff08FAQ\uff09<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aa3b4f4 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"aa3b4f4\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background-color: #fff4f4; border: 1px solid #f5c6cb; color: #721c24; padding: 15px; border-radius: 8px; text-align: center; margin: 20px 0; font-weight: bold;\">\n<i class=\"fa fa-exclamation-triangle\" style=\"margin-right: 10px;\"><\/i>\n\u6cbb\u7642\u306f\u5fc5\u305a\u533b\u5e2b\u306b\u3088\u308b\u6700\u7d42\u7684\u306a\u30b3\u30f3\u30b5\u30eb\u30c6\u30fc\u30b7\u30e7\u30f3\uff08\u8a3a\u5bdf\uff09\u3092\u53d7\u3051\u305f\u5f8c\u306b\u884c\u3063\u3066\u304f\u3060\u3055\u3044\u3002<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-968c093 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"968c093\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 850px; margin: 0 auto; line-height: 1.7; color: #333;\">\n<div style=\"margin-bottom: 25px; border-bottom: 1px solid #eee; padding-bottom: 15px;\">\n<h4 style=\"color: #007bff;\">\u672c\u614b\u6027\u9ad8\u8840\u5727\u75c7\u306b\u5bfe\u3057\u3066\u63a8\u5968\u3055\u308c\u308b\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08WBH\uff09\u306e\u30d7\u30ed\u30c8\u30b3\u30eb\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h4>\n\u672c\u614b\u6027\u9ad8\u8840\u5727\u75c7\u306e\u30d7\u30ed\u30c8\u30b3\u30eb\u3067\u306f\u3001\u76ee\u6a19\u6e29\u5ea6 <strong>38.3 \u00b0C<\/strong> \u3067\u306e <strong>12\u30bb\u30c3\u30b7\u30e7\u30f3<\/strong> \u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5404\u30bb\u30c3\u30b7\u30e7\u30f3\u306f\u7d0445\u5206\u9593\u3067\u300130\u5206\u9593\u306e\u4e0a\u6607\u671f\u306815\u5206\u9593\u306e\u4f11\u606f\u671f\uff08\u30d7\u30e9\u30c8\u30fc\u671f\u306a\u3057\uff09\u3067\u69cb\u6210\u3055\u308c\u307e\u3059\u3002\n\n<\/div>\n<div style=\"margin-bottom: 25px; border-bottom: 1px solid #eee; padding-bottom: 15px;\">\n<h4 style=\"color: #007bff;\">\u6162\u6027\u80cc\u90e8\u75db\uff08\u8170\u75db\u30fb\u80cc\u90e8\u75db\uff09\u306b\u5bfe\u3057\u3066\u63a8\u5968\u3055\u308c\u308bWBH\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h4>\n\u6162\u6027\u80cc\u90e8\u75db\u306b\u5bfe\u3057\u3066\u306f\u3001\u901a\u5e38 <strong>6\u30bb\u30c3\u30b7\u30e7\u30f3<\/strong> \u304c\u63a8\u5968\u3055\u308c\u3001\u76ee\u6a19\u6e29\u5ea6\u306f <strong>38.4 \u00b0C<\/strong> \u3067\u3059\u3002\u5168\u30bb\u30c3\u30b7\u30e7\u30f3\u6642\u9593\u306f\u7d0490\u5206\u3067\u300145\u5206\u9593\u306e\u4e0a\u6607\u671f\u300115\u5206\u9593\u306e\u30d7\u30e9\u30c8\u30fc\u671f\uff08\u7dad\u6301\u671f\uff09\u300130\u5206\u9593\u306e\u4f11\u606f\u671f\u304c\u542b\u307e\u308c\u307e\u3059\u3002\n\n<\/div>\n<div style=\"margin-bottom: 25px; border-bottom: 1px solid #eee; padding-bottom: 15px;\">\n<h4 style=\"color: #007bff;\">\u7dda\u7dad\u7b4b\u75db\u75c7\u304a\u3088\u3073\u5f37\u76f4\u6027\u810a\u690e\u708e\u306b\u5bfe\u3059\u308bWBH\u306e\u30d7\u30ed\u30c8\u30b3\u30eb\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h4>\n\u7dda\u7dad\u7b4b\u75db\u75c7\u3068\u5f37\u76f4\u6027\u810a\u690e\u708e\u306f\u3001\u3044\u305a\u308c\u3082\u901a\u5e38 <strong>6\u30bb\u30c3\u30b7\u30e7\u30f3<\/strong> \u306e\u30d7\u30ed\u30c8\u30b3\u30eb\u306b\u5f93\u3044\u3001\u76ee\u6a19\u6e29\u5ea6\u306f <strong>38.5 \u00b0C<\/strong> \u3067\u3059\u3002\u5168\u30bb\u30c3\u30b7\u30e7\u30f3\u6642\u9593\u306f\u7d0490\u5206\u3067\u300145\u5206\u9593\u306e\u4e0a\u6607\u671f\u300115\u5206\u9593\u306e\u30d7\u30e9\u30c8\u30fc\u671f\u300130\u5206\u9593\u306e\u4f11\u606f\u671f\u3067\u69cb\u6210\u3055\u308c\u307e\u3059\u3002\n\n<\/div>\n<div style=\"margin-bottom: 25px; border-bottom: 1px solid #eee; padding-bottom: 15px;\">\n<h4 style=\"color: #007bff;\">\u304c\u3093\u306e\u88dc\u52a9\u6cbb\u7642\u3068\u3057\u3066\u63a8\u5968\u3055\u308c\u308bWBH\u306e\u30d7\u30ed\u30c8\u30b3\u30eb\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h4>\n\u304c\u3093\u306e\u88dc\u52a9\u6cbb\u7642\uff08\u4f75\u7528\u7642\u6cd5\uff09\u3068\u3057\u3066\u306e\u5834\u5408\u3001\u6df1\u90e8\u4f53\u6e29 <strong>39.0 \u00b0C \u304b\u3089 40.0 \u00b0C<\/strong> \u3092\u76ee\u6a19\u306b <strong>2\u30bb\u30c3\u30b7\u30e7\u30f3\u4ee5\u4e0a<\/strong> \u304c\u5fc5\u8981\u3067\u3059\u3002\u5168\u30bb\u30c3\u30b7\u30e7\u30f3\u6642\u9593\u306f\u6700\u3082\u9577\u304f <strong>3\u6642\u9593\u304b\u30894\u6642\u9593<\/strong> \u306b\u53ca\u3073\u3001\u3053\u308c\u306b\u306f60\u301c90\u5206\u306e\u4e0a\u6607\u671f\u300160\u301c90\u5206\u306e\u30d7\u30e9\u30c8\u30fc\u671f\u3001\u304a\u3088\u307360\u5206\u306e\u4f11\u606f\u671f\u304c\u542b\u307e\u308c\u307e\u3059\u3002\n\n<\/div>\n<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3875720 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"3875720\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 100%; overflow-x: auto; margin: 20px 0;\"> <table style=\"width: 100%; border-collapse: collapse; font-family: sans-serif; min-width: 800px; border: 1px solid #e0e0e0;\"> <thead> <tr style=\"background-color: #2c3e50; color: white; text-align: left;\"> <th style=\"padding: 15px; border: 1px solid #34495e;\">\u9069\u5fdc\u75c7<\/th> <th style=\"padding: 15px; border: 1px solid #34495e;\">\u30bb\u30c3\u30b7\u30e7\u30f3\u6570<\/th> <th style=\"padding: 15px; border: 1px solid #34495e;\">\u76ee\u6a19\u6e29\u5ea6<\/th> <th style=\"padding: 15px; border: 1px solid #34495e;\">\u52a0\u6e29\u6cbb\u7642\uff08\u4e0a\u6607\uff0b\u30d7\u30e9\u30c8\u30fc\uff09<\/th> <th style=\"padding: 15px; border: 1px solid #34495e;\">\u4f11\u606f\u6642\u9593<\/th> <th style=\"padding: 15px; border: 1px solid #34495e;\">\u5408\u8a08\u6642\u9593<\/th> <\/tr> <\/thead> <tbody style=\"color: #333;\"> <tr> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u672c\u614b\u6027\u9ad8\u8840\u5727\u75c7<\/strong><\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">12<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">38.3 \u00b0C<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">30\u5206 (30+0)<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">15\u5206<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u7d0445\u5206<\/strong><\/td> <\/tr> <tr style=\"background-color: #f8f9fa;\"> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u6162\u6027\u80cc\u90e8\u75db\uff08\u8170\u75db\u30fb\u80cc\u90e8\u75db\uff09<\/strong><\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">6<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">38.4 \u00b0C<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">60\u5206 (45+15)<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">30\u5206<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u7d0490\u5206<\/strong><\/td> <\/tr> <tr> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u7dda\u7dad\u7b4b\u75db\u75c7<\/strong><\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">6<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">38.5 \u00b0C<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">60\u5206 (45+15)<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">30\u5206<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u7d0490\u5206<\/strong><\/td> <\/tr> <tr style=\"background-color: #f8f9fa;\"> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u5f37\u76f4\u6027\u810a\u690e\u708e<\/strong><\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">6<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">38.5 \u00b0C<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">60\u5206 (45+15)<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">30\u5206<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u7d0490\u5206<\/strong><\/td> <\/tr> <tr> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u5168\u8eab\u6027\u5f37\u76ae\u75c7<\/strong><\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">15<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">38.3 \u00b0C<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">30\u5206 (30+0)<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">15\u5206<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u7d0445\u5206<\/strong><\/td> <\/tr> <tr style=\"background-color: #f8f9fa;\"> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u5927\u3046\u3064\u75c5\u6027\u969c\u5bb3<\/strong><\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">1\u56de\u4ee5\u4e0a<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">38.5 \u00b0C<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">105-170\u5206<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">30\u5206<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u7d042\u301c3\u6642\u9593<\/strong><\/td> <\/tr> <tr style=\"background-color: #eef2ff;\"> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\"><strong>\u304c\u3093\u306e\u88dc\u52a9\u6cbb\u7642<\/strong><\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">2\u56de\u4ee5\u4e0a<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; text-align: center;\">39.0-40.0 \u00b0C<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">120-180\u5206<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0;\">60\u5206<\/td> <td style=\"padding: 12px; border: 1px solid #e0e0e0; color: #d32f2f;\"><strong>\u7d043\u301c4\u6642\u9593<\/strong><\/td> <\/tr> <\/tbody> <\/table> <\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d0149af animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"d0149af\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background-color: #fff9db; border: 1px solid #ffeeba; color: #856404; padding: 15px; border-radius: 8px; text-align: left; margin: 20px 0; font-style: italic;\"> <strong>\u6ce8\u8a18\uff1a<\/strong>\u3053\u306e\u6587\u66f8\u306f\u3001wIRA\u3092\u7528\u3044\u305f\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08WBH\uff09\u306b\u95a2\u3059\u308b\u7814\u7a76\u3084\u52b9\u679c\u3092\u7db2\u7f85\u3057\u305f\u30ea\u30b9\u30c8\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002 <\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0f3186c e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"0f3186c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-072e6e2 elementor-widget elementor-widget-heading\" data-id=\"072e6e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u53c2\u8003\u6587\u732e\u304a\u3088\u3073\u5f15\u7528<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d13e67b animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"d13e67b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"max-width: 1000px; margin: 0 auto; background: #ffffff; padding: 30px; border: 1px solid #e0e0e0; border-radius: 5px;\"><div id=\"model-response-message-contentr_870bbb496f57ebda\" class=\"markdown markdown-main-panel stronger enable-updated-hr-color\" dir=\"ltr\" aria-live=\"polite\" aria-busy=\"false\"><p data-path-to-node=\"0\">\u53c2\u8003\u6587\u732e\u304a\u3088\u3073\u5f15\u7528<\/p><\/div><ol style=\"line-height: 1.6; color: #555; font-size: 0.9em; font-family: 'Segoe UI', Tahoma, Geneva, Verdana, sans-serif;\"><li style=\"margin-bottom: 10px;\">Ardenne M. von. Moderate Hyperthermie als Behandlungsmethode mit vielen Indikationen. <em>\u00c4rztzeitschr Naturheilverf<\/em> 1994; 5:356-61.<\/li><li style=\"margin-bottom: 10px;\">B\u00e4umler H., Scherf H.P., Aurisch R., et al. Einflu\u00df einer Serie von Infrarot-Ganzk\u00f6rperbestrahlungen auf Flie\u00dfeigenschaften des Blutes und die H\u00e4modynamik. <em>Perfusion<\/em> 1990: 138-43.<\/li><li style=\"margin-bottom: 10px;\">Heckel M. Ganzk\u00f6rper-Hyperthermie und Fiebertherapie, Grundlagen und Praxis. Stuttgart: <em>Hippokrates Verlag<\/em>, 1990.<\/li><li style=\"margin-bottom: 10px;\">Kosaka M., Sugahara T., Schmidt K.L., Simon E. Thermotherapy: Principles and Practice. Heidelberg: <em>Springer Verlag<\/em>, 2000.<\/li><li style=\"margin-bottom: 10px;\">Meffert H., Hecht H.C., G\u00fcnther H., et al. Biophysikalische Ergebnisse des klinischen Tests der IRA-Therm-Hyperthermietechnik der 2. Generation. <em>ThermoMed<\/em> 1990; 6:71-78.<\/li><li style=\"margin-bottom: 10px;\">Schmidt K.L. Hyperthermie und Fieber, Wirkungen bei Mensch und Tier. 2. \u00fcberarb Aufl. Stuttgart: <em>Hippokrates Verlag<\/em>, 1987.<\/li><li style=\"margin-bottom: 10px;\">Vaupel P., Kr\u00fcger W. W\u00e4rmetherapie mit wassergefilterter Infrarot-A-Strahlung, Grundlagen und Anwendungsm\u00f6glichkeiten. 2. \u00fcberarb Aufl. Stuttgart: <em>Hippokrates Verlag<\/em>, 1995.<\/li><li style=\"margin-bottom: 10px;\">Piazena H., Meffert H. Optische Eigenschaften der Haut und die photobiologischen Grundlagen zur Dosierung von IR-Hautbestrahlungen in vivo und in vitro. <em>6. Symposium Licht und Gesundheit<\/em> 2008.<\/li><li style=\"margin-bottom: 10px;\">Zschaeck S. and Beck M. Chapter 8 Whole-Body Hyperthermia in Oncology: Renaissance in the Immunotherapy Era?<\/li><li style=\"margin-bottom: 10px;\">Zhang H, Wang W, Zhang S, Huang W. Comparison of the anti-tumor effects of various whole-body hyperthermia protocols&#8230; <em>Immunol Invest.<\/em> 2005;34(3):245-58.<\/li><li style=\"margin-bottom: 10px;\">Abreu MM, Chocron AF, Smadja DM. From cold to hot: mechanisms of hyperthermia in modulating tumor immunology for enhanced immunotherapy. <em>Front Immunol.<\/em> 2025 Feb 28;16:1487296.<\/li><li style=\"margin-bottom: 10px;\">Bull JMC. et al. Fever-range whole-body thermal therapy combined with cisplatin, gemcitabine, and daily interferon-\u03b1. <em>Journal of Hyperthermia.<\/em> 2008; 24(8): 649-662.<\/li><li style=\"margin-bottom: 10px;\">Weigelin B. Visualization of the immune effect of hyperthermia. <em>ICHO 2021<\/em>, Session: Hyperthermia and immunology.<\/li><li style=\"margin-bottom: 10px;\">Faghihi Moghaddam F, Bakhshandeh M, Mofid B, et al. Clinical effectiveness of combined WBH and EBRT versus EBRT alone&#8230; <em>J Therm Biol.<\/em> 2024 Feb;120:103804.<\/li><li style=\"margin-bottom: 10px;\">Hildebrandt B, Dr\u00e4ger J, Kerner T. et al. Whole-body hyperthermia in the scope of von Ardenne\u2019s systemic cancer multistep therapy (sCMT)&#8230; <em>International Journal of Hyperthermia.<\/em> 2004;3:317\u2013333.<\/li><li style=\"margin-bottom: 10px;\">Atmaca A., Al-Batran S.E., Neumann A., et al. WBH in combination with carboplatin in patients with recurrent ovarian cancer \u2013 a phase II study. <em>Gynecol Oncol<\/em> 2009; 2:384-88.<\/li><li style=\"margin-bottom: 10px;\">Brockow T., et al. A Randomized Controlled Trial on the Effectiveness of Mild Water-filtered Near Infrared WBH&#8230; <em>Clin J Pain<\/em> 2007; 1:67-75.<\/li><li style=\"margin-bottom: 10px;\">Kleef R, Nagy R, Baierl A, et al. Low-dose Ipilimumab plus Nivolumab combined with IL-2 and hyperthermia in cancer patients with advanced disease. <em>Cancer Immunol Immunother.<\/em> 2021;70:1393\u2013403.<\/li><li style=\"margin-bottom: 10px;\">Adachi H., Katsuno M., Waza M., et al. Heat shock proteins in neurodegenerative diseases. <em>Int J Hyperthermia<\/em> 2009; 8:647-54.<\/li><li style=\"margin-bottom: 10px;\">Atmaca A., Al-Batran S.E., Neumann A., et al. Whole-body hyperthermia (WBH) in combination with carboplatin&#8230; <em>Gynecol Oncol<\/em> 2009; 2:384-88.<\/li><li style=\"margin-bottom: 10px;\">Bull J.M., et al. An Update of a Phase II Clinical Trial Using Fever-Range Whole-Body Thermal Therapy (FR-WB-TT)&#8230; <em>Soc for Thermal Med<\/em>, 2007.<\/li><li style=\"margin-bottom: 10px;\">Bull J.M., et al. Fever-range WBH combined with cisplatin, gemcitabine and daily interferon-\u03b1. <em>Int J Hyperthermia<\/em> 2008; 8:649-62.<\/li><li style=\"margin-bottom: 10px;\">Bull J.M., et al. A phase-I-study of optimally-timed Gemcitabine + Cisplatin\/Interferon-a combined with WBH. <em>ESHO 2001<\/em>, Verona, Italy.<\/li><li style=\"margin-bottom: 10px;\">Capitano M., Mace T., Nemeth M., et al. A novel strategy for improving neutrophil recovery following total body irradiation. <em>Soc for Thermal Med<\/em>, 2010.<\/li><li style=\"margin-bottom: 10px;\">Dayanc B.E., Ostberg J.R., Repasky E.A. Enhancement of NK Cell Cytotoxic Activity by Mild Thermal Stress. <em>Soc of Thermal Med<\/em>, 2006.<\/li><li style=\"margin-bottom: 10px;\">Hajto T., Hostanska K. Effect of in vivo hyperthermia on human natural killer cells. <em>Clin Trials J<\/em> 1985; 6:514-20.<\/li><li style=\"margin-bottom: 10px;\">Hattori T., et al. Antitumor effect of WBH with \u03b1-galactosylceramide in a subcutaneous tumor model of colon cancer. <em>Int J Hyperthermia<\/em> 2007; 7:591-98.<\/li><li style=\"margin-bottom: 10px;\">Kisailus A., et al. Thermal Regulation of Antigen Presenting Cells: Use of Hyperthermia as an Adjuvant for Cancer Vaccines. <em>Soc of Thermal Med<\/em>, 2006.<\/li><li style=\"margin-bottom: 10px;\">Multhoff G. Activation of natural killer (NK) cells by heat shock protein 70&#8230; <em>Int J Hyperthermia<\/em> 2009; 3:176-79.<\/li><li style=\"margin-bottom: 10px;\">Peer A.J., et al. Diverse immune mechanisms may contribute to the survival benefit seen in cancer patients receiving hyperthermia. <em>Immunol Res<\/em> 2010; 1-3:137-154.<\/li><li style=\"margin-bottom: 10px;\">Rowe R.W., et al. Fever-range WBH combined with oxaliplatin: A curative regimen in a pre-clinical breast cancer model. <em>Int J Hyperthermia<\/em> 2010; 6:565-76.<\/li><li style=\"margin-bottom: 10px;\">Schencking M., Frese T., Sandholzer H. Behandlung einer Radikulopathie bei oss\u00e4rer Metastasierung durch Infrarot-A-Ganzk\u00f6rperhyperthermie. <em>Forsch Komplementmed<\/em> 2008; 15:273-76.<\/li><li style=\"margin-bottom: 10px;\">Scott G.L., Bull J.M.C., Kochn M. Management of Conscious Sedation&#8230; <em>9th Int Congress on Hyperthermic Oncology<\/em>, 2004.<\/li><li style=\"margin-bottom: 10px;\">Shecterle L.M., Cyr J.A.S. Hyperthermia Aids Patients with Advanced Lung Cancer. <em>Soc of Thermal Med<\/em>, 2006.<\/li><li style=\"margin-bottom: 10px;\">Skitzki J.J., Repasky E.A., Evans S.S. Hyperthermia as an immunotherapy strategy for cancer. <em>Current Opinion in Investigational Drugs<\/em> 2009; 6: 550-58.<\/li><li style=\"margin-bottom: 10px;\">Toyota N., et al. Long-duration, mild whole body hyperthermia with cisplatin: tumour response and kinetics of apoptosis and necrosis&#8230; <em>Int. J. Hyperthermia<\/em> 1997; 5:497-506.<\/li><li style=\"margin-bottom: 10px;\">Wang X.Y., et al. Characterization of heat shock protein 110 and glucose-regulated protein 170 as cancer vaccines&#8230; <em>J of Immunology<\/em> 2001; 165:490-97.<\/li><li style=\"margin-bottom: 10px;\">VanderZee J., et al. Reirradiation combined with hyperthermia in breast cancer recurrences&#8230; <em>Int J Hyperthermia<\/em> 2010; 7:638-48.<\/li><li style=\"margin-bottom: 10px;\">Zagar T.M., et al. Hyperthermia for locally advanced breast cancer. <em>Int J Hyperthermia<\/em> 2010; 7:618-24.<\/li><li style=\"margin-bottom: 10px;\">Zagar T.M., et al. Hyperthermia combined with radiation therapy for superficial breast cancer and chest wall recurrence&#8230; <em>Int J Hyperthermia<\/em> 2010; 7: 612\u201317.<\/li><li style=\"margin-bottom: 10px;\">Sen A., Capitano M., Dommer M., et al. Thermoregulatory responses to mild systemic thermal stress increase tumor perfusion&#8230; <em>Cancer Res.<\/em> 2011; 71(11):3872-3880.<\/li><li style=\"margin-bottom: 10px;\">Koska J., Rovensky J., Zimanova T., Vigas M. Growth hormone and prolactin responses during partial and whole body warm-water immersions. <em>Acta Physiol Scand.<\/em> 2003.<\/li><li style=\"margin-bottom: 10px;\">Vigas M., Rovensky J., Zimanova T., Koska J. Responses of growth hormone and prolactin to local and whole-body application of Piestany mud. <em>Acta Rheumatol<\/em> 2002:31-38.<\/li><li style=\"margin-bottom: 10px;\">Meffert B., Hochmuth O., Steiner M. Effects of multiple mild infrared-induced hyperthermia on central and peripheral pulse waves. <em>North Sea Conference<\/em> 1990.<\/li><li style=\"margin-bottom: 10px;\">Meffert H., Scherf HP., Meffert B. Milde Infrarot-A-Hyperthermie. Auswirkungen von Serienbestrahlungen&#8230; <em>Akt Dermatol<\/em> 1993; 19:142-48.<\/li><li style=\"margin-bottom: 10px;\">Applegate L.A., et al. Induction of the putative protein ferritin by infrared radiation: Implications in skin repair. <em>Int J of Molecular Med<\/em> 2000; 5:247-51.<\/li><li style=\"margin-bottom: 10px;\">Scherf H.P., et al. Wirkung einer einmaligen milden Infrarot-A-Hyperthermie auf K\u00f6rpertemperatur, Herzfrequenz, Blutdruck und Blutviskosit\u00e4t&#8230; <em>Dermatol Monatsschr<\/em> 1989.<\/li><li style=\"margin-bottom: 10px;\">Streffer C. Metabolic changes during and after hyperthermia. <em>Int J Hyperthermia<\/em> 1985; 4:305-319.<\/li><li style=\"margin-bottom: 10px;\">F\u00f6rster J., et al. Infrared-Mediated Hyperthermia is Effective in the Treatment of Scleroderma-Associated Raynaud\u2019s Phenomenon. <em>J Invest Dermatol<\/em> 2005.<\/li><li style=\"margin-bottom: 10px;\">Koska J., Rovensky J., Zimanova T., et al. Sympathoadrenal regulation of circulatory responses to WBH&#8230; <em>Acta Rheumatol<\/em> 2002:23-30.<\/li><li style=\"margin-bottom: 10px;\">Janssen C.W., et al. Whole-Body Hyperthermia for the Treatment of Major Depressive Disorder \u2013 A Randomized Clinical Trial. <em>JAMA Psychiatry<\/em> 2016.<\/li><li style=\"margin-bottom: 10px;\">Tarner I.H., et al. The effect of mild WBH on systemic levels of TNF-alpha, IL-1 beta and IL-6 in patients with ankylosing spondylitis. <em>Clin Rheumatol<\/em> 2009.<\/li><li style=\"margin-bottom: 10px;\">Ettrich U., et al. Milde Ganzk\u00f6rperhyperthermie in Kombination mit station\u00e4rer multimodal orientierter Schmerztherapie&#8230; <em>Orthop\u00e4de<\/em> 2014; 2:165-74.<\/li><li style=\"margin-bottom: 10px;\">Weller E., Ullrich D. Infrarot-A-Hyperthermie-Anwendung bei Patienten cu Analgetica-Abusus wegen chronischer R\u00fcckenschmerzen. <em>95. Kongre\u00df Phys Med<\/em> 1990.<\/li><li style=\"margin-bottom: 10px;\">Morf S., Vesti B.A., Forster A., et al. Microcirculation abnormalities in patients with fibromyalgia \u2013 measured by capillary and laser fluxmetry. <em>Arthritis Res Ther<\/em> 2005.<\/li><li style=\"margin-bottom: 10px;\">Walz J., et al. Ganzk\u00f6rperhyperthermie in der Schmerztherapie \u2013 eine kontrollierte Studie an Patienten mit Fibromyalgiesyndrom. <em>Schmerz<\/em> 2013; 27:38-45.<\/li><li style=\"margin-bottom: 10px;\">Romeyke T., Stummer H. Multi-modal pain therapy of fibromyalgia syndrome with integration of systemic WBH&#8230; <em>J Musculoskel Pain<\/em> 2014; 4:341-55.<\/li><li style=\"margin-bottom: 10px;\">Zauner D., et al. WBH treatment increases interleukin 10 and toll-like receptor 4 expression in patients with ankylosing spondylitis. <em>Int J Hyperthermia<\/em> 2014.<\/li><li style=\"margin-bottom: 10px;\">Lange U., et al. Wirkung iterativer Ganzk\u00f6rperhyperthermie cu wassergefilterter Infrarot-A-Strahlung bei ankylosierender Spondylitis&#8230; <em>Akt Rheumatol<\/em> 2017.<\/li><\/ol><div style=\"margin-top: 30px; padding: 15px; background-color: #f8f9fa; border-left: 4px solid #3498db; font-style: italic;\"><p style=\"margin: 0; font-size: 0.9em;\"><strong>EN:<\/strong> The complete database of over 60 clinical studies on wIRA technology is available upon request.<\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-97dc368 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"97dc368\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><section><p>\u00a0<\/p><\/section><footer>\u00a9 <time>2025<\/time> Romanian Society Oncologic Hyperthermia All rights reserved. Source: Analysis based on scientific literature.<\/footer><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u816b\u760d\u5b66\u304a\u3088\u3073\u4ed6\u75be\u60a3\u306b\u304a\u3051\u308b\u5168\u8eab\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\uff08WBH\uff09\uff1a\u78ba\u7acb\u3055\u308c\u305f\u76f8\u4e57\u52b9\u679c\u3001\u514d\u75ab\u8abf\u7bc0\u3001\u304a\u3088\u3073\u81e8\u5e8a\u7684\u30a8\u30d3\u30c7\u30f3\u30b9 \u516c\u958b\u65e5\uff1a2025\u5e7410\u670813\u65e5 | \u6700\u7d42\u66f4\u65b0\u65e5\uff1a2025\u5e7410\u670813\u65e5 \u8457\u8005 Veronica Iatan,<br \/><a class=\"moretag\" href=\"https:\/\/ardenneiratherm.com\/ja\/clinical-research\/\">+ Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/page-fullwidth_template.php","meta":{"footnotes":""},"class_list":["post-1904","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/ardenneiratherm.com\/ja\/wp-json\/wp\/v2\/pages\/1904","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ardenneiratherm.com\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ardenneiratherm.com\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ardenneiratherm.com\/ja\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ardenneiratherm.com\/ja\/wp-json\/wp\/v2\/comments?post=1904"}],"version-history":[{"count":0,"href":"https:\/\/ardenneiratherm.com\/ja\/wp-json\/wp\/v2\/pages\/1904\/revisions"}],"wp:attachment":[{"href":"https:\/\/ardenneiratherm.com\/ja\/wp-json\/wp\/v2\/media?parent=1904"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}