{"id":990,"date":"2025-10-13T09:59:16","date_gmt":"2025-10-13T09:59:16","guid":{"rendered":"https:\/\/ardenneiratherm.com\/clinical-trials-whole-body-hyperthermia-wira\/"},"modified":"2026-01-17T10:57:15","modified_gmt":"2026-01-17T10:57:15","slug":"kliniska-provningar-hypertermi-ira-onkolog","status":"publish","type":"page","link":"https:\/\/ardenneiratherm.com\/sv\/kliniska-provningar-hypertermi-ira-onkolog\/","title":{"rendered":"Klinisk evidens och forskning: wIRA-hypertermi inom onkologisk praxis"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"990\" class=\"elementor elementor-990 elementor-756\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ea8f7b2 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"ea8f7b2\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInDown&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f3c7e79 elementor-widget elementor-widget-heading\" data-id=\"f3c7e79\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Helkroppshypertermi (WBH) inom onkologi och kliniska indikationer: Synergistiska effekter, immunmodulering och evidensbaserade pr\u00f6vningar<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c02c88e animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"c02c88e\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><header><p><strong><span style=\"color: #6a6a6a;\">Publicerad: <time datetime=\"2025-10-13\">2025-10-13<\/time> | Senast Granskad: <time datetime=\"2025-10-13\">2025-10-13<\/time><\/span><\/strong><\/p><\/header><div class=\"authors\"><p>F\u00f6rfattare:<br \/><a href=\"\/?p=1315\">Veronica Iatan, M.D.<\/a>,<br \/><a href=\"\/?p=1342\">Cristian Gologan, M.Sc.<\/a><\/p><\/div><section class=\"ai-summary\"><p style=\"font-weight: bold; font-style: italic;\"><strong>Helkroppshypertermi (WBH)<\/strong> \u00e4r en systemisk onkologisk strategi som inneb\u00e4r en kontrollerad \u00f6kning av kroppens k\u00e4rntemperatur, ofta med hj\u00e4lp av tekniken <strong>Vattenfiltrerad Infrar\u00f6d Str\u00e5lning A (wIRA)<\/strong>. WBH \u00e4r fr\u00e4mst en <strong>Kemo\/Radio-sensibilisator<\/strong>, som signifikant f\u00f6rb\u00e4ttrar tum\u00f6rperfusion och syres\u00e4ttning, vilket \u00f6kar effektiviteten hos traditionella terapier. Fundamentalt sett fungerar den som en potent <strong>Systemisk Immunmodulator<\/strong>, som mobiliserar V\u00e4rmechockproteiner (VCP) och T-lymfocyter. Denna \u00e5tg\u00e4rd skapar en avg\u00f6rande synergi med avancerad <strong>Immunterapi (ICI)<\/strong> och ger dramatisk, snabb sm\u00e4rtlindring samt en avsev\u00e4rd f\u00f6rb\u00e4ttring av Livskvaliteten (LV) vid olika cancerformer och kroniska tillst\u00e5nd som fibromyalgi.<\/p><\/section><section class=\"disclaimer\"><strong> Medicinsk Ansvarsfriskrivning: Denna artikel \u00e4r endast avsedd f\u00f6r informationssyften och ers\u00e4tter inte p\u00e5 n\u00e5got s\u00e4tt individuell medicinsk r\u00e5dgivning, diagnos eller behandling f\u00f6rskriven av en legitimerad l\u00e4kare.<\/strong><\/section><section><h2>\u00a0<\/h2><\/section><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-805e6aa e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"805e6aa\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-67bd9be elementor-widget elementor-widget-heading\" data-id=\"67bd9be\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">1. Definition av Helkroppshypertermi (WBH) och Terapeutisk Teknik<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-67346b0 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"67346b0\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><p style=\"text-align: left;\"><strong>Helkroppshypertermi (WBH)<\/strong>, eller &#8221;Systemisk Hypertermi&#8221;, definieras som en kontrollerad \u00f6kning av kroppens k\u00e4rntemperatur i terapeutiska syften. Baserat p\u00e5 <strong>spektrumet av effekter fr\u00e5n naturlig feber vid olika temperaturer<\/strong>, differentieras WBH-procedurer p\u00e5 f\u00f6ljande s\u00e4tt:<\/p><ul style=\"text-align: left;\"><li><strong>Mild WBH:<\/strong> &lt; 38,5*\u00b0*C<\/li><li><strong>M\u00e5ttlig WBH:<\/strong> 38,5*\u00b0C &#8211; 40,5 *\u00b0**C<\/li><li><strong>Extrem WBH:<\/strong> &gt; 40,5*\u00b0*C<\/li><\/ul><p style=\"text-align: left;\">Specifikt \u00f6kar Mild och M\u00e5ttlig WBH <strong>blodfl\u00f6det (perfusionen),<\/strong> stimulerar metabolismen, minskar muskeltonus och <strong class=\"key-term\">stimulerar immunf\u00f6rsvaret.<\/strong><\/p><p style=\"text-align: left;\"><a title=\"Tekniska Detaljer om von Ardenne IRATHERM\u00ae 1000M WBH wIRA enheten\" href=\"https:\/\/ardenneiratherm.com\/sv\/ardenne-iratherm-hypertermiapparat\/\"><strong>von Ardenne IRATHERM<\/strong>\u00ae <strong>1000M WBH wIRA hypertermi enheten<\/strong><\/a> anv\u00e4nder uteslutande <strong>vattenfiltrerad Infrar\u00f6d Str\u00e5lning A (wIRA), djupt penetrerande och hudv\u00e4nlig<\/strong> (utan IR-B \/ IR-C) f\u00f6r detta \u00e4ndam\u00e5l. Dess \u00f6ppna, icke-klaustrofobiska design s\u00e4kerst\u00e4ller j\u00e4mn str\u00e5lningsintensitet \u00f6ver patientens hela yta (rygg) och erbjuder anv\u00e4ndaren optimal, patientspecifik v\u00e4rmetillf\u00f6rsel n\u00e4r det g\u00e4ller b\u00e5de position och intensitet.<\/p><p style=\"text-align: left;\">Vattenfiltrerad Infrar\u00f6d Str\u00e5lning A motsvarar naturlig soltermisk str\u00e5lning och utg\u00f6r den tekniska grunden f\u00f6r en j\u00e4mn och skonsam v\u00e4rmetillf\u00f6rsel.<span class=\"citation\">[1, 5, 7, 8]<\/span>.<\/p><p style=\"text-align: left;\">Genom att anv\u00e4nda von Ardenne IRATHERM<sup>\u00ae<\/sup> 1000-principen, utvecklad och bevisad under mer \u00e4n 30 \u00e5r, kunde <a title=\"Prof. Manfred von Ardenne - Bidrag\" href=\"\/?p=5\">Prof. Manfred von Ardenne<\/a> fysiskt och tekniskt \u00e5terskapa denna termiska str\u00e5lning och g\u00f6ra den industriellt tillg\u00e4nglig f\u00f6r permanent medicinsk anv\u00e4ndning genom helkroppshypertermi.<\/p><div class=\"mceTemp\" style=\"text-align: left;\">\u00a0<\/div><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6c924fa elementor-invisible elementor-widget elementor-widget-image\" data-id=\"6c924fa\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;zoomIn&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/ardenneiratherm.com\/wp-content\/uploads\/2025\/10\/von-Ardenne-Iratherm-10000-WBH-wIRA-hyperthermia-device-wIRA.jpg\" title=\"\" alt=\"von Ardenne Iratherm 10000 WBH wIRA hyperthermia-device-wIRA\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-48fd6d3 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"48fd6d3\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-aafa804 elementor-widget elementor-widget-heading\" data-id=\"aafa804\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">2. Vetenskapliga Grunder och Systemiska Effekter<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-672df30 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"672df30\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><section>\n<p style=\"text-align: left;\">Helkroppshypertermi (WBH) har utvecklats till en klinisk strategi f\u00f6rankrad i solida biofysiska och fysiologiska principer. Inom onkologin ligger fokus fr\u00e4mst p\u00e5 <b>m\u00e5ttlig hypertermi<\/b> och <b>feberomr\u00e5deshypertermi (FRH-WBH)<\/b>, vilka \u00e4r erk\u00e4nda terapeutiska modaliteter f\u00f6r ett brett spektrum av indikationer.<span class=\"citation\">[1, 3]<\/span><\/p>\n\n<p style=\"text-align: left;\">Den tekniska f\u00f6ruts\u00e4ttningen f\u00f6r en homogen och skonsam v\u00e4rme\u00f6verf\u00f6ring s\u00e4kerst\u00e4lls genom system som utnyttjar <b>vattenfiltrerad infrar\u00f6d-A-str\u00e5lning (wIRA)<\/b>. Ing\u00e5ende biofysiska studier har validerat <strong>denna tekniks f\u00f6rm\u00e5ga att garantera en djupverkande och kontrollerad v\u00e4vnadsuppv\u00e4rmning<\/strong>, med h\u00e4nsyn till hudens optiska egenskaper och den fotobiologiska dosimetrin [5,7,8].<\/p>\n\n<p style=\"text-align: left;\">P\u00e5 fysiologisk niv\u00e5 genererar WBH fundamentala systemiska effekter som optimerar den terapeutiska milj\u00f6n:<\/p>\n\n<ol style=\"text-align: left;\">\n\t<li><strong>F\u00f6rb\u00e4ttrad blodreologi:<\/strong> Exponering f\u00f6r wIRA-WBH har en gynnsam inverkan p\u00e5 <b>blodfl\u00f6desegenskaper och hemodynamik [2]<\/b>. Detta st\u00f6djer nyckelmekanismen f\u00f6r <b>f\u00f6rb\u00e4ttrad tum\u00f6rperfusion<\/b> \u2013 en kritisk f\u00f6ruts\u00e4ttning f\u00f6r framg\u00e5ngsrika systemiska terapier.<\/li>\n\t<li><strong>Systemisk biologisk aktivering:<\/strong> WBH inducerar ett termiskt stressrespons som utl\u00f6ser en kaskad av biologiska processer, inklusive <b>modulering av det endokrina systemet<\/b> och en <b>accelererad metabolism<\/b>. <span class=\"citation\">[6, 4]<\/span>.<\/li>\n<\/ol>\n\n<p style=\"text-align: left;\">Genom dessa mekanismer fungerar WBH som en potent <strong class=\"key-term\">systemisk immunmodulator<\/strong>, vilket optimerar <strong class=\"key-term\">tum\u00f6rmikromilj\u00f6n (TME)<\/strong> och <strong>potentierar effekten av avancerade onkologiska terapier<\/strong>.<\/p>\n<\/section><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-73d38c1 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"73d38c1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4061817 elementor-widget elementor-widget-heading\" data-id=\"4061817\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">3. Nyckelmekanismer (Molekyl\u00e4ra, Fysiologiska och Immunologiska)<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-22327e2 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"22327e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><p style=\"text-align: left;\">WBH:s terapeutiska effekter \u00e4r komplexa, f\u00f6rmedlade av f\u00f6r\u00e4ndringar p\u00e5 cellul\u00e4r, immunologisk och fysiologisk niv\u00e5:<\/p><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5638fef animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"5638fef\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><h3 style=\"text-align: left;\">A. Synergi med Kemoterapi och Str\u00e5lbehandling (Kemo\/Radio-sensibilisator)<\/h3><ul style=\"text-align: left;\"><li><strong>Optimering av Tum\u00f6rmikromilj\u00f6n (TMM):<\/strong> WBH f\u00f6rb\u00e4ttrar <strong>tum\u00f6rens blodtillf\u00f6rsel<\/strong> och <strong>syres\u00e4ttning<\/strong>, och reverserar d\u00e4rmed tum\u00f6rhypoxin. Detta \u00e4r avg\u00f6rande, eftersom v\u00e4l syresatta cancerceller \u00e4r signifikant k\u00e4nsligare f\u00f6r f\u00f6rst\u00f6relse genom <strong>Kemoterapi<\/strong> (KT) och <strong>Str\u00e5lbehandling<\/strong> (ST).[9,41]<\/li><li><strong>KT\/ST Effektivitet:<\/strong> Hypertermi fungerar som en <strong class=\"key-term\">Kemo &amp; Radio Sensibilisator<\/strong>, f\u00f6rb\u00e4ttrar syretillf\u00f6rseln till tum\u00f6ren (radio-sensibiliserande effekt) och \u00f6kar effektiviteten hos l\u00e4kemedel som Cisplatin, Gemcitabin och Carboplatin.[12,16,36]<\/li><\/ul><h3 style=\"text-align: left;\">\u00a0<\/h3><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3119e45 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"3119e45\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><section><h3 style=\"text-align: left;\">B. Induktion av ett Kraftfullt Antitum\u00f6r-Immunsvar (Immunmodulering)<\/h3><p style=\"text-align: left;\">WBH \u00e4r en potent aktivator av kroppens f\u00f6rsvarssystem:<\/p><ul style=\"text-align: left;\"><li><strong>V\u00e4rmechockproteiner (VCP):<\/strong> Termisk stress stimulerar syntesen och fris\u00e4ttningen av <b>VCP70(HSP70)<\/b>. Dessa proteiner fungerar som &#8221;farasignaler&#8221; och markerar tum\u00f6rceller f\u00f6r en f\u00f6rst\u00e4rkt attack av immunsystemets <b>Cytotoxiska T-lymfocyter (CTL)<\/b>.<span class=\"citation\">[9, 10, 29]<\/span>.<\/li><li><strong>Aktivering av Nyckelimmunceller:<\/strong> Temperaturintervallet <b>39\u201343\u00b0C<\/b> \u00f6kar aktiviteten hos <b>Naturliga M\u00f6rdarceller (NK-celler)<\/b>\u00a0och fr\u00e4mjar aktiviteten hos <b>Hj\u00e4lpar- och Cytotoxiska T-lymfocyter, Dendritiska Celler\u00a0<\/b>och <b>Makrofager<\/b>, samtidigt som det <span style=\"text-decoration: underline;\">potentiellt skadar immunsuppressiva celler<\/span>.<span class=\"citation\">[9, 10, 11, 25, 26]<\/span>.<\/li><li><strong>\u00d6kning av T-lymfocyter:<\/strong> FOH-WBH kan <b>signifikant \u00f6ka (t.ex. 3 g\u00e5nger)<\/b>\u00a0<b>populationen av cytotoxiska T-lymfocyter i lymfoida organ, vilket st\u00e4rker den systemiska antitum\u00f6r-immunattacken[10]<\/b><\/li><li><strong>Vacciner och APC:<\/strong> WBH kan reglera funktionen hos Antigenpresenterande Celler (APC) och \u00f6ka effektiviteten hos cancervacciner, inklusive de baserade p\u00e5 VCP110 och GRP170.\u00a0[37, 28].<\/li><\/ul><\/section><section><h2 style=\"text-align: left;\">\u00a0<\/h2><\/section><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bbbd880 animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"bbbd880\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e99507b elementor-widget elementor-widget-heading\" data-id=\"e99507b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">4. Klinisk Evidens och Synergi i Multimodal Terapi<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e6a66ba animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"e6a66ba\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><h3 style=\"text-align: left;\">A. Synergi med Immunterapi (Immunkontrollpunktsh\u00e4mmare &#8211; ICH)<\/h3><p style=\"text-align: left;\">En retrospektiv fallserie med 131 patienter med avancerat karcinom (Steg IV) unders\u00f6kte ett multimodalt protokoll som inkluderade <b>Helkroppshypertermi<\/b> ut\u00f6ver immunkontrollpunktsh\u00e4mmare (Ipilimumab, Nivolumab) och IL-2.[18]<\/p><p style=\"text-align: left;\"><strong>Huvudslutsats:<\/strong> WBH wIRA definierades som en <b>integrerad och v\u00e4sentlig komponent<\/b>\u00a0som *maximerar det antitum\u00f6riala immunsvar. <strong>WBH aktiverar och mobiliserar T-lymfocyter (inducerar VCP70 och fris\u00e4tter tum\u00f6rantigener);<\/strong> kontrollpunktsh\u00e4mmarna &#8221;sl\u00e4pper sedan bromsen&#8221; fr\u00e5n dessa f\u00f6r-aktiverade T-lymfocyter, vilket leder till ovanligt h\u00f6ga frekvenser av gynnsamt kliniskt svar vid avancerad sjukdom.[18]<\/p><h3 style=\"text-align: left;\">\u00a0<\/h3><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-464662f animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"464662f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><section><h3 style=\"text-align: left;\">B. Kliniska Till\u00e4mpningar i Olika Cancerformer<\/h3><ul style=\"text-align: left;\"><li><strong>Pankreascancer:<\/strong> Fas I-II protokoll som anv\u00e4nder Mild WBH (FOH-WBH) i kombination med Kemoterapi och Interferon-alfa visade <b>minst 50 % tum\u00f6rregression hos n\u00e4stan h\u00e4lften av de behandlingsresistenta patienterna<\/b>.[4,22[<\/li><li><strong>Br\u00f6stcancer (\u00c5terfall):<\/strong> WBH i kombination med re-bestr\u00e5lning eller Str\u00e5lbehandling har visat effekt vid lokalt avancerad br\u00f6stcancer och \u00e5terfall i br\u00f6stv\u00e4ggen, st\u00f6dd av randomiserade data.[39,40]<\/li><li><strong>\u00c4ggstockscancer:<\/strong> WBH i kombination med <strong>Carboplatin<\/strong> studerades i en Fas II-pr\u00f6vning f\u00f6r \u00e5terkommande \u00e4ggstockscancer.[16,20]<\/li><li><strong>Kolorektal Cancer:<\/strong> WBH wIRA anv\u00e4ndes i samband med von Ardennes Systemiska Flerskiktscancerterapi (sCMT) i kombination med Kemoterapi i en Fas I\/II-pr\u00f6vning.[15]<\/li><\/ul><\/section><section><h2 style=\"text-align: left;\">\u00a0<\/h2><\/section><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4cb34f6 e-con-full animated-slow e-flex elementor-invisible e-con e-child\" data-id=\"4cb34f6\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c7ca566 elementor-widget elementor-widget-heading\" data-id=\"c7ca566\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">5. Snabb Sm\u00e4rtlindring och Betydande F\u00f6rb\u00e4ttring av Livskvaliteten (LV)<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8ec3c40 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"8ec3c40\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><p style=\"text-align: left;\">Patienter kan uppleva snabb sm\u00e4rtlindring och en f\u00f6rb\u00e4ttring av det allm\u00e4nna v\u00e4lbefinnandet, vilket observerades i Dr. Bulls studie och, i synnerhet, i den senaste Fas III-kliniska studien av Sahinbas et al.<\/p><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cfebbf0 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"cfebbf0\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><h3>Fas III Klinisk Studie (2024) f\u00f6r Skelettmetastaser<\/h3><div class=\"container\"><div class=\"section\"><section><span dir=\"auto\">\u00c5r\u00a0<\/span><a title=\"Fas III Studie Sahinbas 2024\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0306456524000226\" target=\"_blank\" rel=\"noopener\"><span dir=\"auto\">2024 publicerade Sahinbas och kollegor en Fas III-studie<\/span><\/a><span dir=\"auto\"> om bensm\u00e4rta orsakad av skelettmetastaser, huvudsakligen fr\u00e5n br\u00f6st- och prostatacancer, med anv\u00e4ndning av WBH wIRA Iratherm hypertermienheter som komplement till ST.<\/span><span dir=\"auto\">Enligt denna studie hade endast ST-gruppen den mest intensiva sm\u00e4rtan. Studien slutf\u00f6rdes efter att totalt 61 patienter inkluderats, 5 \u00e5r efter den initiala inskrivningen (april 2016 \u2013 februari 2021). I slut\u00e4ndan visade frekvensen av Komplett Svar (KS) i ST + WBH-gruppen den mest signifikanta skillnaden j\u00e4mf\u00f6rt med endast ST: <strong>47,4 % mot 5,3 %<\/strong>, respektive, <strong>inom 2 m\u00e5nader efter behandlingen<\/strong> (P-v\u00e4rde &lt; 0,05). <strong>Tiden till fullst\u00e4ndig sm\u00e4rtlindring var 10 dagar f\u00f6r ST + WBH-gruppen, medan detta slutm\u00e5l inte uppn\u00e5ddes i gruppen med endast ST.<\/strong> Sm\u00e4rtprogression eller stabil sjukdom observerades hos h\u00e4lften av patienterna i ST-gruppen inom 4 veckor efter behandlingen. D\u00e4remot var <strong>denna po\u00e4ng n\u00e4ra noll hos patienter med ST + WBH inom tv\u00e5 m\u00e5nader efter behandlingen<\/strong>.<\/span><strong class=\"sub-title\"><span dir=\"auto\">Slutsatser:\u00a0<\/span><\/strong><span dir=\"auto\">\u00a0WBH plus ST visade en signifikant \u00f6kning av sm\u00e4rtlindring och en kortare svarstid j\u00e4mf\u00f6rt med endast ST hos patienter med metastatiska skelettskador.<\/span><\/section><\/div><\/div><div class=\"table-scroll-wrapper\"><table border=\"1\"><thead><tr><th><span dir=\"auto\">LV\/Sm\u00e4rtf\u00f6rb\u00e4ttringsindikator<\/span><\/th><th><span dir=\"auto\">ST Monoterapi<\/span><\/th><th><span dir=\"auto\">ST + Hypertermi (WBH wIRA)<\/span><\/th><th><span dir=\"auto\">P\u00e5verkan p\u00e5 LV<\/span><\/th><\/tr><\/thead><tbody><tr><td><strong><span dir=\"auto\">Frekvens av Komplett Svar (KS) vid 2 m\u00e5nader.<\/span><\/strong><span dir=\"auto\">\u00a0(noll sm\u00e4rtpo\u00e4ng)<\/span><\/td><td><strong>5,3 %<\/strong><\/td><td><strong>47,4 %<\/strong><\/td><td><span dir=\"auto\">\u00a0<\/span><strong><span dir=\"auto\">894 % \u00d6kning<\/span><\/strong><span dir=\"auto\">\u00a0i sannolikheten f\u00f6r fullst\u00e4ndig sm\u00e4rteliminering.<\/span><\/td><\/tr><tr><td><strong><span dir=\"auto\">Tid till fullst\u00e4ndig sm\u00e4rtlindring<\/span><\/strong><\/td><td><span dir=\"auto\">uppn\u00e5ddes ej<\/span><\/td><td><span dir=\"auto\">10 dagar<\/span><\/td><td><span dir=\"auto\"><strong>&#8221;Signifikant och Snabb&#8221;<\/strong> Nytta<\/span><\/td><\/tr><tr><td><strong><span dir=\"auto\">Varaktighet av Sm\u00e4rtlindring\u00a0<\/span><\/strong><\/td><td><span dir=\"auto\">Median: <strong>28 dagar\/4 veckor<\/strong> hos h\u00e4lften av patienterna<\/span><\/td><td><span dir=\"auto\">Median: <strong>Uppn\u00e5ddes ej vid 24 veckor<\/strong><\/span><\/td><td><span dir=\"auto\">Varaktigheten av lindringen \u00e4r <strong>sex g\u00e5nger l\u00e4ngre<\/strong>, vilket minskar beroendet av sm\u00e4rtstillande medel.<\/span><\/td><\/tr><\/tbody><\/table><\/div><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e97cd55 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"e97cd55\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><p style=\"text-align: left;\">I j\u00e4mf\u00f6relse med en <a title=\"Fas III Studie Chi MS et al. 2017\" href=\"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360-3016(17)33930-5\" target=\"_blank\" rel=\"noopener\">\u00a0Liknande Fas III-studie publicerad av Chi MS et al<\/a><span dir=\"auto\">\u00a0. (2017) med lokoregional RF-hypertermi, var f\u00f6rdelarna (<em>i termer av LV och sm\u00e4rtreduktion)<\/em> uppn\u00e5dda med WBH wIRA hypertermi signifikant b\u00e4ttre \u2013 Resultat fr\u00e5n RF HT + ST studien:<\/span><\/p><div class=\"table-scroll-wrapper\" style=\"text-align: left;\"><table border=\"1\"><thead><tr><th><span dir=\"auto\">LV\/Sm\u00e4rtf\u00f6rb\u00e4ttringsindikator<\/span><\/th><th><span dir=\"auto\">ST Monoterapi<\/span><\/th><th><span dir=\"auto\">ST + Hypertermi (HT)<\/span><\/th><th>P\u00e5verkan p\u00e5 LV<\/th><\/tr><\/thead><tbody><tr><td><strong><span dir=\"auto\">Frekvens av Komplett Svar (KS) vid 3 M\u00e5nader.<\/span><\/strong><span dir=\"auto\">\u00a0(noll sm\u00e4rtpo\u00e4ng)<\/span><\/td><td><strong>7,1 %<\/strong><\/td><td><strong>37,9 %<\/strong><\/td><td><span dir=\"auto\"><strong>533 % \u00d6kning<\/strong> i sannolikheten f\u00f6r fullst\u00e4ndig sm\u00e4rtlindring.<\/span><\/td><\/tr><tr><td><strong><span dir=\"auto\">Varaktighet av Sm\u00e4rtlindring<\/span><\/strong><\/td><td><span dir=\"auto\">Median: <strong>55 dagar\/7,9 veckor<\/strong><\/span><\/td><td><span dir=\"auto\">Median: <strong>Uppn\u00e5ddes ej vid 24 veckor<\/strong><\/span><\/td><td><span dir=\"auto\">Varaktigheten av lindringen *tredubblas*, vilket minskar beroendet av sm\u00e4rtstillande medel.<\/span><\/td><\/tr><\/tbody><\/table><\/div><p style=\"text-align: left;\">\u00a0<\/p><p style=\"text-align: left;\">Sammanfattningsvis bekr\u00e4ftar den konsoliderade vetenskapliga evidensen (fr\u00e5n grundl\u00e4ggande studier av wIRA-tekniken till viktiga Fas III-kliniska pr\u00f6vningar) WBH:s roll som en adjuvant behandling med en m\u00e5ngfacetterad inverkan inom onkologi: <strong>den \u00f6kar effektiviteten av KT\/ST, aktiverar det systemiska immunsystemet (inklusive synergin med Immunterapi) och f\u00f6rb\u00e4ttrar drastiskt sm\u00e4rtkontrollen och LV<\/strong> hos cancerpatienter.<\/p><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2b9b952 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"2b9b952\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9003cfd elementor-widget elementor-widget-heading\" data-id=\"9003cfd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\n6. Systemiska Fysiologiska F\u00f6rdelar och Terapeutisk Potential i Andra Patologier<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0307397 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"0307397\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><p>Den skonsamma, kontrollerade v\u00e4rmen som tillf\u00f6rs av WBH med wIRA-str\u00e5lning utl\u00f6ser komplexa termoreglerande reaktioner som genererar breda systemiska f\u00f6rdelar, vilket ut\u00f6kar den terapeutiska potentialen bortom onkologi:<\/p><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f8b16cd animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"f8b16cd\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\">\n<div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \">\n<div class=\"wpb_wrapper\">\n<div class=\"section\">\n<div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\">\n<div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header>\n<h3 style=\"text-align: left;\">A. R\u00f6relseapparaten och klinisk sm\u00e4rtbehandling<\/h3>\n<p style=\"text-align: left;\">Helkroppshypertermi (WBH) uppvisar h\u00f6g klinisk relevans vid behandling av kroniska sm\u00e4rtsyndrom genom att modulera muskeltonus och optimera mikrocirkulationen:<\/p>\n\n<ul>\n\t<li style=\"text-align: left;\"><strong>Dorsalgi (Kronisk ryggsm\u00e4rta):<\/strong> Klinisk evidens tyder p\u00e5 att mild WBH som komplement till multimodal station\u00e4r sm\u00e4rtterapi ger signifikanta f\u00f6rdelar f\u00f6r patienter med ospecifik kronisk l\u00e4ndryggssm\u00e4rta (dorsalgi).[53,54]<\/li>\n\t<li style=\"text-align: left;\"><strong>Fibromyalgisyndrom (FMS):<\/strong> WBH \u00e4r en validerad adjuvant behandling vid FMS. Randomiserade kontrollerade studier har p\u00e5visat effekten av mild wIRA-WBH inom ramen f\u00f6r standardiserad multimodal rehabilitering, med m\u00e4tbar reduktion av <strong>sm\u00e4rtintensitet<\/strong> och f\u00f6rb\u00e4ttring av <strong>psykiskt v\u00e4lbefinnande<\/strong>. Denna terapeutiska effekt \u00e4r delvis kopplad till optimering av mikrocirkulationen, en central patofysiologisk faktor hos FMS-patienter.[55]<\/li>\n\t<li style=\"text-align: left;\"><strong>Ankyloserande spondylit (AS \/ Bechterews sjukdom):<\/strong> WBH har p\u00e5visat betydande immunmodulerande effekter vid AS. Studier rapporterar att WBH \u00f6kar niv\u00e5erna av antiinflammatoriska mediatorer s\u00e5som <strong>Interleukin-10<\/strong> (IL-10) och modulerar proinflammatoriska cytokiner som TNF-\u03b1. Detta indikerar en gynnsam roll i kontrollen av den kroniska systemiska inflammationen vid detta tillst\u00e5nd.[58,59,52]<\/li>\n\t<li style=\"text-align: left;\"><strong>Raynauds fenomen vid systemisk skleros:<\/strong> Infrar\u00f6d-baserad hypertermi har visat sig vara effektiv vid behandling av vasokonstriktiva symtom associerade med sklerodermi-relaterat Raynauds fenomen, vilket bekr\u00e4ftar systemets vaskul\u00e4ra f\u00f6rdelar.[49]<\/li>\n<\/ul>\n<\/header><\/div>\n<\/header><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b0c1b89 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"b0c1b89\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><h3 style=\"text-align: left;\">B. Kardiovaskul\u00e4r och Cirkulationsh\u00e4lsa \u2764\ufe0f<\/h3><p style=\"text-align: left;\">F\u00f6rutom att f\u00f6rb\u00e4ttra tum\u00f6rperfusionen har WBH specifika effekter p\u00e5 cirkulationssystemet:<\/p><ul style=\"text-align: left;\"><li><strong>Essentiell Hypertoni:<\/strong> En serie studier har unders\u00f6kt anv\u00e4ndningen av Mild IR-A hypertermi hos patienter med h\u00f6gt blodtryck (WHO Steg I och II). Resultaten tyder p\u00e5 att serietill\u00e4mpningar kan p\u00e5verka positivt *centrala och perifera pulsv\u00e5gor, blodtrycket och <b>blodviskositeten<\/b>, vilket bekr\u00e4ftar WBH:s roll som ett icke-farmakologiskt fysioterapi-alternativ.[44.47]<\/li><\/ul><h3 style=\"text-align: left;\">\u00a0<\/h3><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ce4fdb9 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"ce4fdb9\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \" style=\"text-align: left;\"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><h3 style=\"text-align: left;\">C. Neuroendokrina och Psykologiska Effekter<\/h3><p style=\"text-align: left;\">WBH involverar kroppens neuroendokrina system och p\u00e5verkar hum\u00f6r och metabolism:<\/p><ul><li style=\"text-align: left;\"><strong>Egentlig Depression (ED):<\/strong> En randomiserad klinisk pr\u00f6vning visade att en enda WBH-session kan fungera som ett snabbverkande antidepressivt medel, vilket leder till en minskning av depressiva symtom under flera veckor. Denna effekt \u00e4r relaterad till den v\u00e4rmeinducerade aktiveringen av immun- och inflammatoriska v\u00e4gar som p\u00e5verkar hj\u00e4rnan.[51]<\/li><li style=\"text-align: left;\"><strong>Hormonell Modulering (Endokrinologi):<\/strong> WBH stimulerar <b>Hypotalamus-Hypofys-Binjureaxeln (HPA)<\/b> och p\u00e5verkar hormonniv\u00e5erna. Studier har dokumenterat svar fr\u00e5n <b>Tillv\u00e4xthormon<\/b> och <b>Prolaktin<\/b> under helkroppshypertermi, vilket belyser dess inverkan p\u00e5 endokrin reglering.[42,43]<\/li><li style=\"text-align: left;\"><strong>Metabolism och Cellul\u00e4rt Svar:<\/strong> WBH accelererar den basala \u00e4mnesoms\u00e4ttningen. P\u00e5 cellul\u00e4r niv\u00e5 p\u00e5verkar v\u00e4rme pO2-kinetiken och \u00e4r associerad med syntesen av skyddande proteiner som <b>ferritin<\/b>\u00a0i huden, vilket st\u00f6der v\u00e4vnadsreparation.[46,48]<\/li><\/ul><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-91f7153 elementor-invisible elementor-widget elementor-widget-image\" data-id=\"91f7153\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;zoomIn&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/ardenneiratherm.com\/wp-content\/uploads\/2025\/10\/von-Ardenne-Iratherm-10000-WBH-wIRA-hyperthermia-device-summary.jpg\" title=\"\" alt=\"von Ardenne Iratherm 10000 WBH wIRA hyperthermia-device-summary\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ae37e3c e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"ae37e3c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a7dda12 elementor-widget elementor-widget-heading\" data-id=\"a7dda12\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Vanliga Fr\u00e5gor (FAQ) om Rekommenderade WBH-sessioner och M\u00e5ltemperaturer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aa3b4f4 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"aa3b4f4\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><p><i>Behandlingen b\u00f6r endast utf\u00f6ras efter slutgiltigt samr\u00e5d med en l\u00e4kare<\/i><\/p><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-968c093 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"968c093\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><div><h4>Vilket \u00e4r det rekommenderade helkroppshypertermi (WBH) protokollet f\u00f6r Essentiell Hypertoni?<\/h4><div><p>Protokollet f\u00f6r Essentiell Hypertoni rekommenderar 12 sessioner med en m\u00e5ltemperatur p\u00e5 38,3 \u00b0C. Varje session varar cirka 45 minuter, inklusive 30 minuters temperaturh\u00f6jningsfas och 15 minuters \u00e5terh\u00e4mtningsfas (utan plat\u00e5fas).<\/p><\/div><\/div><div><h4>Vilka \u00e4r de rekommenderade WBH-parametrarna f\u00f6r kronisk ryggsm\u00e4rta (Dorsalgi)?<\/h4><div><p>F\u00f6r Dorsalgi rekommenderas vanligtvis 6 sessioner, med ett m\u00e5l p\u00e5 38,4 \u00b0C. Den totala sessionstiden \u00e4r cirka 90 minuter, inklusive 45 minuters h\u00f6jning, 15 minuters plat\u00e5fas och 30 minuters \u00e5terh\u00e4mtning.<\/p><\/div><\/div><div><h4>Vilket \u00e4r WBH-protokollet f\u00f6r Fibromyalgi och Ankyloserande Spondylit?<\/h4><div><p>B\u00e5de Fibromyalgi och Ankyloserande Spondylit f\u00f6ljer vanligtvis ett protokoll med 6 sessioner, med ett m\u00e5l p\u00e5 38,5 \u00b0C. Den totala sessionstiden \u00e4r cirka 90 minuter, inklusive 45 minuters h\u00f6jning, 15 minuters plat\u00e5 och 30 minuters \u00e5terh\u00e4mtning.<\/p><\/div><\/div><div><h4>Vilket \u00e4r det rekommenderade protokollet f\u00f6r WBH som Adjuvant Terapi vid Cancer?<\/h4><div><p>Som adjuvant terapi f\u00f6r cancer kr\u00e4ver protokollet 2 eller fler sessioner med en central kroppstemperatur p\u00e5 mellan 39,0 \u00b0C och 40,0 \u00b0C. Den totala sessionstiden \u00e4r den l\u00e4ngsta, och varierar mellan 3 och 4 timmar, vilket inkluderar 60\u201390 minuter f\u00f6r h\u00f6jningsfasen, 60\u201390 minuter f\u00f6r plat\u00e5fasen och 60 minuter f\u00f6r \u00e5terh\u00e4mtningsfasen.<\/p><\/div><\/div><div class=\"table-scroll-wrapper\"><table width=\"1151\"><tbody><tr><td width=\"278\">\u00a0<\/td><\/tr><\/tbody><\/table><\/div><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3875720 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"3875720\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><div><div class=\"wpb_content_element \"><div><div><div><div class=\"wpb_content_element \"><div><div><p>\u00a0<\/p><\/div><\/div><div class=\"table-scroll-wrapper\"><table width=\"1151\"><tbody><tr><td width=\"278\">Indikation<\/td><td width=\"99\">Antal Sessioner<\/td><td width=\"135\">M\u00e5ltemperatur<\/td><td colspan=\"2\" width=\"309\">Behandlingstid<br \/>H\u00f6jningsfas\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Plat\u00e5fas<\/td><td width=\"164\">\u00c5terh\u00e4mtningstid<br \/>\u00c5terh\u00e4mtningsfas<\/td><td width=\"164\"><strong>Total Tid<\/strong><br \/><strong>WBH-session<\/strong><\/td><\/tr><tr><td rowspan=\"2\" width=\"278\">Essentiell Hypertoni<\/td><td rowspan=\"2\" width=\"99\">12<\/td><td rowspan=\"2\" width=\"135\">38,3 \u00b0C<\/td><td colspan=\"2\" width=\"309\"><strong>30 min<\/strong><\/td><td rowspan=\"2\" width=\"164\">15 min<\/td><td rowspan=\"2\" width=\"164\"><strong>~ 45 min<\/strong><\/td><\/tr><tr><td width=\"155\">30 min<\/td><td width=\"155\">0 min<\/td><\/tr><tr><td rowspan=\"2\" width=\"278\">Dorsalgi<\/td><td rowspan=\"2\" width=\"99\">6<\/td><td rowspan=\"2\" width=\"135\">38,4 \u00b0C<\/td><td colspan=\"2\" width=\"309\"><strong>60 min<\/strong><\/td><td rowspan=\"2\" width=\"164\">30 min<\/td><td rowspan=\"2\" width=\"164\"><strong>~ 90 min<\/strong><\/td><\/tr><tr><td width=\"155\">45 min<\/td><td width=\"155\">15 min<\/td><\/tr><tr><td rowspan=\"2\" width=\"278\">Fibromyalgi<\/td><td rowspan=\"2\" width=\"99\">6<\/td><td rowspan=\"2\" width=\"135\">38,5 \u00b0C<\/td><td colspan=\"2\" width=\"309\"><strong>60 min<\/strong><\/td><td rowspan=\"2\" width=\"164\">30 min<\/td><td rowspan=\"2\" width=\"164\"><strong>~ 90 min<\/strong><\/td><\/tr><tr><td width=\"155\">45 min<\/td><td width=\"155\">15 min<\/td><\/tr><tr><td rowspan=\"2\" width=\"278\">Ankyloserande Spondylit<\/td><td rowspan=\"2\" width=\"99\">6<\/td><td rowspan=\"2\" width=\"135\">38,5 \u00b0C<\/td><td colspan=\"2\" width=\"309\"><strong>60 min<\/strong><\/td><td rowspan=\"2\" width=\"164\">30 min<\/td><td rowspan=\"2\" width=\"164\"><strong>~ 90 min<\/strong><\/td><\/tr><tr><td width=\"155\">45 min<\/td><td width=\"155\">15 min<\/td><\/tr><tr><td rowspan=\"2\" width=\"278\">Systemisk Skleros<\/td><td rowspan=\"2\" width=\"99\">15<\/td><td rowspan=\"2\" width=\"135\">38,3 \u00b0C<\/td><td colspan=\"2\" width=\"309\"><strong>30 min<\/strong><\/td><td rowspan=\"2\" width=\"164\">15 min<\/td><td rowspan=\"2\" width=\"164\"><strong>~ 45 min<\/strong><\/td><\/tr><tr><td width=\"155\">30 min<\/td><td width=\"155\">0 min<\/td><\/tr><tr><td rowspan=\"2\" width=\"278\">Egentlig Depression<\/td><td rowspan=\"2\" width=\"99\">1+<\/td><td rowspan=\"2\" width=\"135\">38,5 \u00b0C<\/td><td colspan=\"2\" width=\"309\"><strong>105 -170 min<\/strong><\/td><td rowspan=\"2\" width=\"164\">30 min<\/td><td rowspan=\"2\" width=\"164\"><strong>~ 2-3 <\/strong><strong>timmar<\/strong><\/td><\/tr><tr><td width=\"155\">45-110 min<\/td><td width=\"155\">60 min<\/td><\/tr><tr><td rowspan=\"2\" width=\"278\">Adjuvant Cancerterapi<\/td><td rowspan=\"2\" width=\"99\">2+<\/td><td rowspan=\"2\" width=\"135\">39,0-40,0 \u00b0C<\/td><td colspan=\"2\" width=\"309\"><strong>120-180 min<\/strong><\/td><td rowspan=\"2\" width=\"164\">60 min<\/td><td rowspan=\"2\" width=\"164\"><strong>~ 3-4 <\/strong><strong>timmar<\/strong><\/td><\/tr><tr><td width=\"155\">60-90 min<\/td><td width=\"155\">60-90 min<\/td><\/tr><\/tbody><\/table><\/div><\/div><\/div><div id=\"ut-row-inner-68e7a7d03e7dd\" class=\"vc_row wpb_row vc_inner vc_row-fluid ut-row-inner-68e7a7d03e7ec\" style=\"text-align: center;\"><div class=\"wpb_column vc_column_container vc_col-sm-6\"><div id=\"ut-column-inner-68e7a7d03eb05\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"wpb_content_element\"><div id=\"ut_bi_68e7a7d03ebdb\" class=\"bklyn-big-icon-wrap\"><div class=\"bklyn-big-icon bklyn-big-icon-square\">\u00a0<\/div><p class=\"bklyn-big-icon-title\">\u00a0<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d0149af animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"d0149af\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><p>OBS: Denna artikel \u00e4r inte en utt\u00f6mmande lista \u00f6ver studier och effekter av WBH wIRA<\/p><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0f3186c e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"0f3186c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-072e6e2 elementor-widget elementor-widget-heading\" data-id=\"072e6e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Vetenskapliga publikationer i urval<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d13e67b animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"d13e67b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><section><ol><li style=\"text-align: left;\">Ardenne M. von. Moderate Hyperthermie als Behandlungsmethode mit vielen Indikationen. \u00c4rztzeitschr Naturheilverf 1994; 5:356-61.<\/li><li style=\"text-align: left;\">B\u00e4umler H., Scherf H.P., Aurisch R., et al. Einflu\u00df einer Serie von Infrarot-Ganzk\u00f6rperbestrahlungen auf Flie\u00dfeigenschaften des Blutes und die H\u00e4modynamik. Perfusion 1990: 138-43.<\/li><li style=\"text-align: left;\">Heckel M. Ganzk\u00f6rper-Hyperthermie und Fiebertherapie, Grundlagen und Praxis. Stuttgart: Hippokrates Verlag, 1990.<\/li><li style=\"text-align: left;\">Kosaka M., Sugahara T., Schmidt K.L., Simon E. Thermotherapy: Principles and Practice. Heidelberg: Springer Verlag, 2000.<\/li><li style=\"text-align: left;\">Meffert H., Hecht H.C., G\u00fcnther H., et al. Biophysikalische Ergebnisse des klinischen Tests der IRA-Therm-Hyperthermietechnik der 2. Generation. ThermoMed 1990; 6:71-78.<\/li><li style=\"text-align: left;\">Schmidt K.L. 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Milde Ganzk\u00f6rperhyperthermie in Kombination mit station\u00e4rer multimodal orientierter Schmerztherapie&#8230; Orthop\u00e4de 2014; 2:165-74.<\/li><li style=\"text-align: left;\">Weller E., Ullrich D. Infrarot-A-Hyperthermie-Anwendung bei Patienten mit Analgetica-Abusus wegen chronischer R\u00fcckenschmerzen. Vortrag auf dem 95. Kongre\u00df der Gesellschaft f\u00fcr Phys Med und Rehab 5.10.1990.<\/li><li style=\"text-align: left;\">Morf S., Vesti B.A., Forster A., et al. Microcirculation abnormalities in patients with fibromyalgia \u2013 measured by capillary and laser fluxmetry. Arthritis Res Ther 2005; 7:R209-16.<\/li><li style=\"text-align: left;\">Walz J., Hinzmann J., Haase I., Witte T. Ganzk\u00f6rperhyperthermie in der Schmerztherapie \u2013 eine kontrollierte Studie an Patienten mit Fibromyalgiesyndrom. Schmerz 2013; 27:38-45.<\/li><li style=\"text-align: left;\">Romeyke T., Stummer H. Multi-modal pain therapy of fibromyalgia syndrome with integration of systemic whole-body hyperthermia&#8230; J Musculoskel Pain 2014; 4:341-55.<\/li><li style=\"text-align: left;\">Zauner D., Quehenberger F., Hermann J., et al. Whole body hyperthermia treatment increases interleukin 10 and toll-like receptor 4 expression in patients with ankylosing spondylitis: A pilot study. Int J Hyperthermia 2014; 6:393-401.<\/li><li style=\"text-align: left;\">Lange U., M\u00fcller-Ladner U., Dischereit G. Wirkung iterativer Ganzk\u00f6rperhyperthermie mit wassergefilterter Infrarot-A-Strahlung bei ankylosierender Spondylitis&#8230; Akt Rheumatol 2017; 2:122-128.<\/li><\/ol><\/section><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-97dc368 animated-slow elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"97dc368\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"wpb_column vc_column_container vc_col-sm-4\" style=\"text-align: center;\"><div id=\"ut-column-inner-68e7a7d03c96a\" class=\"vc_column-inner vc_column-inner-nested \"><div class=\"wpb_wrapper\"><div class=\"section\"><div class=\"wpb_content_element \"><header id=\"ut_header_68e7a7d03d95c\" class=\"section-header ut-no-title-linebreak-mobile pt-style-2 header-center header-tablet-center header-mobile-center\"><div class=\"lead \" style=\"text-align: center;\" data-delay=\"0\"><header><section><p>\u00a0<\/p><\/section><footer>\u00a9 <time>2025<\/time> Romanian Society Oncologic Hyperthermia All rights reserved. Source: Analysis based on scientific literature.<\/footer><\/header><\/div><\/header><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Helkroppshypertermi (WBH) inom onkologi och kliniska indikationer: Synergistiska effekter, immunmodulering och evidensbaserade pr\u00f6vningar Publicerad: 2025-10-13 | Senast Granskad: 2025-10-13 F\u00f6rfattare:Veronica Iatan, M.D.,Cristian Gologan, M.Sc. Helkroppshypertermi (WBH) \u00e4r en systemisk onkologisk strategi som inneb\u00e4r en kontrollerad \u00f6kning av kroppens k\u00e4rntemperatur, ofta med hj\u00e4lp av tekniken Vattenfiltrerad Infrar\u00f6d Str\u00e5lning A (wIRA). WBH \u00e4r fr\u00e4mst en Kemo\/Radio-sensibilisator, som<br \/><a class=\"moretag\" href=\"https:\/\/ardenneiratherm.com\/sv\/kliniska-provningar-hypertermi-ira-onkolog\/\">+ Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/page-fullwidth_template.php","meta":{"footnotes":""},"class_list":["post-990","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/ardenneiratherm.com\/sv\/wp-json\/wp\/v2\/pages\/990","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ardenneiratherm.com\/sv\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ardenneiratherm.com\/sv\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ardenneiratherm.com\/sv\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ardenneiratherm.com\/sv\/wp-json\/wp\/v2\/comments?post=990"}],"version-history":[{"count":0,"href":"https:\/\/ardenneiratherm.com\/sv\/wp-json\/wp\/v2\/pages\/990\/revisions"}],"wp:attachment":[{"href":"https:\/\/ardenneiratherm.com\/sv\/wp-json\/wp\/v2\/media?parent=990"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}